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licarin A

Basic information Safety Supplier Related

licarin A Basic information

Product Name:
licarin A
Synonyms:
  • licarin A
  • 4-[(2S)-2,3-Dihydro-7-methoxy-3β-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-2-methoxyphenol
  • NSC 370989
  • Phenol, 4-[(2R,3R)-2,3-dihydro-7-methoxy-3-methyl-5-(1E)-1-propen-1-yl-2-benzofuranyl]-2-methoxy-
  • 2-Methoxy-4-((2R,3R)-7-methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)phenol
CAS:
51020-86-1
MF:
C20H22O4
MW:
326.39
Mol File:
51020-86-1.mol
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licarin A Chemical Properties

storage temp. 
4°C, protect from light
form 
Solid
color 
White to off-white
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licarin A Usage And Synthesis

Biological Activity

Licarin A ((+)-Licarin A), which can be isolated from a variety of plants, significantly reduces dinitrophenylhydrazine-human serum albumin (DNP-HSA)-stimulated RBL-2H3 cells. It has anti-allergic effect and reduces TNF-α and PGD2 production, and COX-2 expression.

in vitro

Licarin A is found in plants such as Aristolochia taliscana , Machilus thunbergii and Myristica fragrans , which are used as spices and in folk medicines for nervous and digestive disorders. It also exhibits anti-inflammatory effects.
Licarin A (5-20 μM) reduces TNF-α and prostaglandin D2 (PGD2) secretion via the inhibition of PKCα/βII and p38 MAPK pathways. Licarin A treatment tends to reduce phosphorylated PKCα/βII and p38 MAPK protein levels.

licarin ASupplier

Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
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meilunui@163.com
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Email
y.liu@mail.biobiopha.com
Chengdu Biopurify Phytochemicals Ltd.
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+86-028-82633397 18982077548
Email
cwb1@biopurify.cn
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
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tauto@tautobiotech.com
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Email
3003855609@qq.com