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defibrotide

Basic information Safety Supplier Related

defibrotide Basic information

Product Name:
defibrotide
Synonyms:
  • defibrotide
  • Dasovas
  • Defibrinotide
  • Fraction p
  • Noravid
  • Prociclide
  • defibrotide USP/EP/BP
  • Defibrotide Impurity 2
CAS:
83712-60-1
MW:
0
Mol File:
Mol File
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Safety Information

Toxicity
LD50 intraperitoneal in dog: > 600mg/kg
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defibrotide Usage And Synthesis

Description

Defibrotide is an antithrornbotic, partially-depolymerized polydeoxyribonucleotide obtained from bovine lungs. It is reported to be useful in the treatment of myocardial and severe lower limb ischemia, renal failure due to thrombotic microangiopathy, and thrombophlebitis, and in the prophylaxis of deep vein thrombosis, possibly via PCI2 stimulation.

Originator

Crinos (Italy)

brand name

NORAVID; PROCICLIDE

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