(-)-Arctigenin
(-)-Arctigenin Basic information
- Product Name:
- (-)-Arctigenin
- Synonyms:
-
- (3R,4R)-4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-2(3H)-FURANONE
- 2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-,(3R,4R)
- 2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]
- ARCTIGENIN:2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-,(3R,4R)
- 2(3H)-Furanone,4-[(3,4-dimethoxyphenyl) methyl]
- dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-,(3R,4R)-
- ARCTIGENIN
- ARCTIGENIN(P)
- CAS:
- 7770-78-7
- MF:
- C21H24O6
- MW:
- 372.41
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Inhibitors
- Miscellaneous Natural Products
- Protein Kinase
- Mol File:
- 7770-78-7.mol
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(-)-Arctigenin Chemical Properties
- Melting point:
- 98.0 to 102.0 °C
- Boiling point:
- 567.0±45.0 °C(Predicted)
- Density
- 1.227±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO: 34 mg/mL with heating and sonicating, soluble
- form
- solid
- pka
- 10.03±0.20(Predicted)
- color
- White to Light yellow
- λmax
- 280nm(EtOH)(lit.)
- InChI
- InChI=1S/C21H24O6/c1-24-18-7-5-13(11-20(18)26-3)8-15-12-27-21(23)16(15)9-14-4-6-17(22)19(10-14)25-2/h4-7,10-11,15-16,22H,8-9,12H2,1-3H3/t15-,16+/m0/s1
- InChIKey
- NQWVSMVXKMHKTF-JKSUJKDBSA-N
- SMILES
- O1C[C@H](CC2=CC=C(OC)C(OC)=C2)[C@@H](CC2=CC=C(O)C(OC)=C2)C1=O
- LogP
- 2.470 (est)
- CAS DataBase Reference
- 7770-78-7(CAS DataBase Reference)
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- RTECS
- LY9247000
- HS Code
- 2932.20.4500
MSDS
- Language:English Provider:SigmaAldrich
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(-)-Arctigenin Usage And Synthesis
Chemical Properties
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Arctium lappa, Trachelospermi chinensis, Rhizoma Cynanchum, Saussurea jellyfish and Forsythia suspensa.
Uses
Arctigenin is a plant ligan associated with anticancer and antioxidant properties.
Definition
ChEBI: (-)-Arctigenin is a lignan.
Biological Activity
Antioxidant, anti-inflammatory, antiproliferative and antiviral agent. Inhibits LPS-induced iNOS expression via inhibition of I κ B α phosphorylation and p65 nuclear translocation (IC 50 = 10 nM). Inhibits HIV-1 replication in vitro . Also potently inhibits MKK1 (IC 50 = 0.5 nM) and provides neuroprotection by binding to kainate receptors.
storage
-20°C (desiccate)
(-)-ArctigeninSupplier
Weifang Huazhi Biological Technology Co., Ltd. Gold
- Tel
- 025-84430028 13815430202
- sale02@cqherb.com
Sichuan Hongen Plant Technology Co., Ltd. Gold
- Tel
- +86-17340288373
- 2370026295@qq.com
J & K SCIENTIFIC LTD.
- Tel
- 18210857532; 18210857532
- jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
future industrial shanghai co., ltd
- Tel
- 400-0066400 13621662912
- sales@jonln.com
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(-)-Arctigenin(7770-78-7)Related Product Information
- Dihydromyrcenol
- Methanol
- Kresoxim-methyl
- Methyl acrylate
- Tribenuron methyl
- CHLOROPHOSPHONAZO III
- Methylparaben
- ARCTIGENIN-O-BETA-D-GLUCOPYRANOSIDE,ARCTIGENIN-O-BETA-D-GLUCOPYRANOSIDE,ARCTIGENIN-O-BETA-D-GLUCOPYRANOSIDE
- Methyl salicylate
- Methyl
- 4-(3,4-DIMETHOXYPHENYL)BUTYRIC ACID
- Masoprocol
- MATAIRESINOL
- tracheloside
- Arctigenin methyl ether,Arctigenin methyl ether,Arctigenin methyl ether
- 2-(3-HYDROXY-BENZYL)-BUTYRIC ACID
- ENTEROLACTONE
- (-)-Arctigenin