tubotaiwine
tubotaiwine Basic information
- Product Name:
- tubotaiwine
- Synonyms:
-
- tubotaiwine
- 2,16-Didehydrocondyfolan-16-carboxylic acid methyl ester
- Methyl (14beta)-2,16-didehydrocondyfolan-16-carboxylate
- NSC 306222
- Tubotaiwin
- 20(S)-tubotaiwine
- 3,5-Ethano-3H-pyrrolo[2,3-d]carbazole-6-carboxylic acid, 4-ethyl-1,2,3a,4,5,7-hexahydro-, methyl ester, (3S,3aR,4S,5S,11bS)-
- CAS:
- 6711-69-9
- MF:
- C20H24N2O2
- MW:
- 324.42
- Mol File:
- 6711-69-9.mol
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tubotaiwine Chemical Properties
- Boiling point:
- 467.7±45.0 °C(Predicted)
- Density
- 1.26±0.1 g/cm3(Predicted)
- pka
- 8.48±0.60(Predicted)
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tubotaiwine Usage And Synthesis
Uses
Tubotaiwine ((+)-Tubotaiwine), an alkaloid, has beneficial effect on cadmium (Cd) induced hypertension in rats. Tubotaiwine regulates systolic, diastolic and mean arterial blood pressure of the Cd exposed rats. Tubotaiwine reduces arterial stiffness, inhibits of oxidative stress and increases vascular remodeling[1].
Definition
ChEBI: A natural product found in Alstonia spatulata.
References
[1] Liwei Gao, et al. Protective Effect of Tubotaiwine on Cadmium-Induced Hypertension in Rats through Reduction in Arterial Stiffness and Vascular Remodeling. Dokl Biochem Biophys. 2021 Sep;500(1):368-375. DOI:10.1134/S1607672921050136
tubotaiwineSupplier
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