VERATROSINE
VERATROSINE Basic information
- Product Name:
- VERATROSINE
- Synonyms:
-
- VERATROSINE
- 14,15,16,17-Tetradehydro-23β-hydroxyveratraman-3β-yl β-D-glucopyranoside
- 3-O-beta-D-Glucopyranosylveratramine
- Veratramine 3-glucoside
- Veratramine 3-O-glucoside
- β-D-Glucopyranoside, (3β,23β)-14,15,16,17-tetradehydro-23-hydroxyveratraman-3-yl
- (2R,3R,4S,5S,6R)-2-(((3S,6aR,11aS,11bR)-9-((S)-1-((2S,3R,5S)-3-Hydroxy-5-methylpiperidin-2-yl)ethyl)-10,11b-dimethyl-2,3,4,6,6a,11,11a,11b-octahydro-1H-benzo[a]fluoren-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
- CAS:
- 475-00-3
- MF:
- C33H49NO7
- MW:
- 571.74
- Mol File:
- 475-00-3.mol
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VERATROSINE Chemical Properties
- Melting point:
- 237.8-239.7℃ (methanol )
- Boiling point:
- 740.7±60.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- solubility
- DMSO: soluble
- form
- A solid
- pka
- 12.91±0.70(Predicted)
- color
- Off-white to yellow
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Safety Information
- Hazardous Substances Data
- 475-00-3(Hazardous Substances Data)
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VERATROSINE Usage And Synthesis
Description
This glucoalkaloid occurs with pseudojervine in Veratrum viride. The melting point given above is that obtained in an open tube; in an evacuated tube it is 276-8°C. The base is laevorotatory having [α]25D - 53.0° (EtOH-CHCI3) and on hydrolysis with boiling, dilute HCl it furnishes P+)-glucose and Veratramine (q.v.).
Uses
Veratrosine is a steroidal alkaloid obtained from Veratrum dahuricum which has displayed antitumor and anti-platelet activity, inhibiting the hedgehog pathway in NIH?/3T3 cells
References
Jacobs, Craig.,]. Biol. Chem., 155,565 (1944)
VERATROSINESupplier
Chembest Research Laboratories Limited
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- +86-21-20908456
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Chengdu Biopurify Phytochemicals Ltd.
- Tel
- +86-028-82633397 18982077548
- cwb1@biopurify.cn
Shanghai Winherb Medical Technology Co., Ltd.
- Tel
- 400-400-186-5138 13341702378
- winherb@126.com
Shanghai Tauto Biotech Co., Ltd.
- Tel
- 021-51320588
- tauto@tautobiotech.com
Chengdu Herbpurify Co.Ltd.
- Tel
- 18302802153 18981717076
- 2355253619@qq.com
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