Basic information Safety Supplier Related

VERATROSINE

Basic information Safety Supplier Related

VERATROSINE Basic information

Product Name:
VERATROSINE
Synonyms:
  • VERATROSINE
  • 14,15,16,17-Tetradehydro-23β-hydroxyveratraman-3β-yl β-D-glucopyranoside
  • 3-O-beta-D-Glucopyranosylveratramine
  • Veratramine 3-glucoside
  • Veratramine 3-O-glucoside
  • β-D-Glucopyranoside, (3β,23β)-14,15,16,17-tetradehydro-23-hydroxyveratraman-3-yl
CAS:
475-00-3
MF:
C33H49NO7
MW:
571.74
Mol File:
475-00-3.mol
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VERATROSINE Chemical Properties

Melting point:
237.8-239.7℃ (methanol )
Boiling point:
740.7±60.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
solubility 
DMSO: soluble
form 
A solid
pka
12.91±0.70(Predicted)
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Safety Information

Hazardous Substances Data
475-00-3(Hazardous Substances Data)
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VERATROSINE Usage And Synthesis

Description

This glucoalkaloid occurs with pseudojervine in Veratrum viride. The melting point given above is that obtained in an open tube; in an evacuated tube it is 276-8°C. The base is laevorotatory having [α]25D - 53.0° (EtOH-CHCI3) and on hydrolysis with boiling, dilute HCl it furnishes P+)-glucose and Veratramine (q.v.).

Uses

Veratrosine is a steroidal alkaloid obtained from Veratrum dahuricum which has displayed antitumor and anti-platelet activity, inhibiting the hedgehog pathway in NIH?/3T3 cells

References

Jacobs, Craig.,]. Biol. Chem., 155,565 (1944)

VERATROSINESupplier

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