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Metomidate Hydrochloride

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Metomidate Hydrochloride Basic information

Product Name:
Metomidate Hydrochloride
Synonyms:
  • 1H-Imidazole-5-carboxylic acid, 1-(1-phenylethyl)-, methyl ester, monohydrochloride
  • Nsc168403
  • Metomidate Hydrochloride (50 mg) (methyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate hydrochloride)
  • 1H-Imidazole-5-carboxylic acid,1-(1-phenylethyl)-,methyl ester,hydrochloride(1:1)
  • Methyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate hydrochloride
  • Metomidate Hydrochloride (methyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate hydrochloride) (1268772)
  • 1H-Imidazole-4-carboxylicacid,1-(10-bromophenyl)-
  • 1-(1-phenylethyl)-1H-Imidazole-5-carboxylic acid methyl ester hydrochloride (1:1)
CAS:
35944-74-2
MF:
C13H14N2O2.ClH
MW:
266.727
Mol File:
35944-74-2.mol
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Metomidate Hydrochloride Chemical Properties

Melting point:
173-174 °C
storage temp. 
Sealed in dry,Room Temperature
solubility 
Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
InChI
InChI=1S/C13H14N2O2.ClH/c1-10(11-6-4-3-5-7-11)15-9-14-8-12(15)13(16)17-2;/h3-10H,1-2H3;1H
InChIKey
NZEDTZKNEKPBGR-UHFFFAOYSA-N
SMILES
N1(C=NC=C1C(=O)OC)C(C)C1=CC=CC=C1.Cl
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Safety Information

HS Code 
2933290000
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Metomidate Hydrochloride Usage And Synthesis

Uses

Metomidate Hydrochloride is used as an anesthetic for veterinary use.

Uses

Metomidate hydrochloride is an imidazole-based, nonbarbiturate hypnotic drug primarily used as an immersion sedation and anesthetic agent in freshwater and marine finfish. Adding sedatives, such as metomidate hydrochloride, to shipping water may improve fish survival rates and the percentage of fish in saleable condition.

Mechanism of action

As mentioned earlier, metomidate has been suggested to block the stress response. Imidazole anesthetics (e.g., metomidate and etomidate) interrupt cortisol synthesis in mammals by suppressing the enzyme 11-beta-hydroxylase, which is necessary for cortisol production.

Metomidate HydrochlorideSupplier

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Artis Biotech Co. Ltd.
Tel
19138486554 18582380095
Email
sales@artisbio.com
parabiochem
Tel
025-83453382-8005
Email
sale@parabiochem.com
BePharm Ltd
Tel
400-685-9117
Email
market@bepharm.com
Amadis Chemical Company Limited
Tel
571-89925085
Email
sales@amadischem.com
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