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Lincomycin hydrochloride monohydrate

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Lincomycin hydrochloride monohydrate Basic information

Product Name:
Lincomycin hydrochloride monohydrate
Synonyms:
  • d-erythro-d-galacto-octopyranoside,methyl6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-,monohydrochloride,hemihydrate
  • frademicina
  • lincocinhydrochloridehydrate
  • lincomycin,hydrochloride,hemihydrate
  • lincomycin,hydrochloridehydrate
  • methyl6,8-dideoxy-6-(1-methyl-4-propyl-2-d-erythro-d-galacto-octopyranosid
  • mycivin
  • lincocin hydrochlohydrate
CAS:
7179-49-9
MF:
C18H37ClN2O7S
MW:
461.01
EINECS:
615-424-7
Product Categories:
  • Antibiotics
  • Interferes with Protein SynthesisAnalytical Standards
  • LSpectrum of Activity
  • MLSMore...Close...
  • Alphabetic
  • Antibacterial
  • Antibiotics A to
  • Antibiotics G-MAntibiotics
  • Chemical Structure
  • Chemical Structure Class
  • L - ZAntibiotics
  • MacrolidesAntibiotics
  • Mechanism of Action
  • LINCOCIN
Mol File:
7179-49-9.mol
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Lincomycin hydrochloride monohydrate Chemical Properties

Melting point:
156-158°
alpha 
D25 +143° (water)
storage temp. 
Sealed in dry,2-8°C
solubility 
Very soluble in water, slightly soluble in ethanol (96 per cent), very slightly soluble in acetone.
form 
Solid
color 
White to Almost white
Merck 
14,5500
Major Application
clinical testing
InChIKey
LFZGYTBWUHCAKF-DCNJEFSFSA-N
SMILES
Cl[H].[H]O[H].CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O
CAS DataBase Reference
7179-49-9(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-24/25
WGK Germany 
2
RTECS 
RH6315500
HS Code 
29419090
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Lincomycin hydrochloride monohydrate Usage And Synthesis

Chemical Properties

White or almost white, crystalline powder.

Uses

antibacterial

brand name

Lincocin (Pharmacia & Upjohn).

Contact allergens

Lincomycin is an antibiotic of the lincosanide group，active against Gram-positive bacteria. Occupational exposure occurs in poultry and pig breeders

in vivo

Lincomycin (25 and 50 mg/kg, intravenously) depresses neuromuscular transmission to a degree which depended on stimulation frequencies in the rabbit sciatic nerve-gastrocnemius muscle preparation[3].

Animal Model:Adult albino New Zealand rabbits weighing 2.5-3.5 kg[3].
Dosage:25 and 50 mg/kg.
Administration:Intravenously.
Result:Depressed neuromuscular transmission.

Lincomycin hydrochloride monohydrate Preparation Products And Raw materials

Raw materials

Sodium hydroxideHydrochloric acidAmmonium hydroxideAcetone1-ButanolAmmonium sulfateOxalic acidAmmonium nitrate

Preparation Products

Clindamycin hydrochloride

Lincomycin hydrochloride monohydrateSupplier

J & K SCIENTIFIC LTD.
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Energy Chemical
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021-021-58432009 400-005-6266
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1-(800)-881-8210
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inquiries@lgmpharma.com
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Lincomycin hydrochloride monohydrate(7179-49-9)Related Product Information