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URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT

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URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT Basic information

Product Name:
URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT
Synonyms:
  • Uridine 5′-diphosphate sodium salt from
  • UDP 2NA
  • URIDINE 5'-DIPHOSPHATE DISODIUM SALT
  • URIDINE 5'-DIPHOSPHORIC ACID DISODIUM SALT
  • Uridine-5' diphosphate(UDP)disodium salt
  • Uridine 5′-(trihydrogen diphosphate) sodium salt from Saccharomyces cerevisiae,UDP sodium salt, Uridine 5′-(trihydrogen pyrophosphate) sodium salt
  • uridine 5'-diphosphate sodium from*yeast
  • URIDINE-5'-DIPHOSPHATE, SODIUM SALT 98+%
CAS:
21931-53-3
MF:
C9H12N2Na2O12P2
MW:
448.12
EINECS:
999-999-2
Product Categories:
  • Bases & Related Reagents
  • Carbohydrates & Derivatives
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Nucleotides
  • Pharmaceuticals
Mol File:
21931-53-3.mol
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URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT Chemical Properties

storage temp. 
-20°C
solubility 
H2O: soluble100 mg/mL, clear, colorless to very faintly yellow
form 
Powder
color 
White
Water Solubility 
Soluble in water to 100mM
Stability:
Hygroscopic
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-68/22-68/20/21/22-20/21/22
Safety Statements 
36/37
WGK Germany 
3
HS Code 
29349990
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URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT Usage And Synthesis

Description

Uridine-5'-diphosphate disodium salt is a potent, selective P2Y6 receptor native agonist (EC50=300 nM; pEC50=6.52 for human P2Y6 receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis.

Uses

A phosphorylated derivative of the nucleoside Uridine. It is further phosphorylated by nucleoside diphosphokinase to form the triphosphate analogue.

Uses

Uridine 5''-Diphosphate Sodium Salt is a potentially useful P2Y receptor agonist. It can be used in biological study and use in chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination.

Biochem/physiol Actions

P2Y receptor agonist.

in vitro

Uridine-5'-diphosphate disodium salt (100 μM; for 15 min) significantly induces microglial CCL2 and CCL3 mRNA expression.

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