2-Fluorocinnamic acid Chemical Properties

Melting point:

178-180 °C(lit.)

Boiling point:

290°C (rough estimate)

Density 

1.2247 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

form 

Crystalline Powder of Flakes

pka

4.31±0.10(Predicted)

color 

White

BRN 

1863963

InChI

InChI=1S/C9H7FO2/c10-8-4-2-1-3-7(8)5-6-9(11)12/h1-6H,(H,11,12)

InChIKey

IOUDZAFBPDDAMK-AATRIKPKSA-N

SMILES

C(O)(=O)C=CC1=CC=CC=C1F

CAS DataBase Reference

451-69-4(CAS DataBase Reference)

NIST Chemistry Reference

2-Propenoic acid, 3-(2-fluorophenyl)-(451-69-4)

EPA Substance Registry System

2-Propenoic acid, 3-(2-fluorophenyl)- (451-69-4)

Safety Information

Hazard Codes 

Xi,C

Risk Statements 

36/37/38-34

Safety Statements 

37/39-26-45-36/37/39-27-24/25

WGK Germany 

3

RTECS 

GD9081000

HazardClass 

IRRITANT

HS Code 

29163990

Storage Class

11 - Combustible Solids

MSDS

• Language:English Provider:2-Fluorocinnamic acid
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Fluorocinnamic acid Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

2-Fluorocinnamic acid was used in the synthesis of acrylamide.

Synthesis

There are various methods for synthesizing o-fluorocinnamic acid, such as Perkin's method, Knoevenagel's method, o-fluorobenzaldehyde-acetone method, o-fluorobenzaldehyde-vinyl ketone method, o-fluorobenzaldehyde-acetic acid method, styrene-carbon tetrachloride method, Styrene-carbon monoxide method, styrene-carbon dioxide method, phenylchloromethane-anhydrous sodium acetate method, halogenated benzene-acrylic acid method, cinnamaldehyde oxidation method and so on. Most of the above methods have no practical industrial application value or have been eliminated due to high energy consumption, heavy pollution, high cost and low yield. At present, the main methods for the industrial production of o-fluorocinnamic acid are Perkin's method and styrene-carbon tetrachloride method. The author reviews and evaluates the progress of the synthesis of o-fluorocinnamic acid based on the classification of reaction materials.

2-Fluorocinnamic acid(451-69-4)Related Product Information

• N-BUTYL CINNAMATE
• Cinnamic acid
• alpha-Methylcinnamic acid
• trans-Cinnamic acid
• Methyl cinnamate
• 4-Hydroxycinnamic acid
• 2-Nitrocinnamic acid
• Ethyl cinnamate
• Citric acid
• Ascoric Acid
• 4-Fluorocinnamic acid
• 2-BROMO-5-FLUOROCINNAMIC ACID,2-BROMO-5-FLUOROCINNAMIC ACID
• 3-CHLORO-4-FLUOROCINNAMIC ACID,3-CHLORO-4-FLUOROCINNAMIC ACID
• 2,3,4,5,6-PENTAFLUOROCINNAMIC ACID
• 3,5-DIFLUOROCINNAMIC ACID
• 2,3,5-TRIFLUOROCINNAMIC ACID
• 3-Fluorocinnamicacid
• 3,4,5-TRIFLUOROCINNAMIC ACID