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CORYNOLINE

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CORYNOLINE Basic information

Product Name:
CORYNOLINE
Synonyms:
  • CORYNOLINE
  • [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-5b,13-
  • dimethyl-, (5bR,6S,12bR)-
  • (5bR)-5bα,13-Dimethyl-5bα,6,7,12bα,13,14-hexahydro[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine-6β-ol
  • 13-Methylchelidonan-11β-ol
  • CORYNOLINE(P)
  • Corynoline, 98%, from Corydalis bungeana Turcz.
  • [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol, 5b,6,7,12b,13,14-hexahydro-5b,13-dimethyl-, (5bR,6S,12bR)-
CAS:
18797-79-0
MF:
C21H21NO5
MW:
367.4
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
18797-79-0.mol
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CORYNOLINE Chemical Properties

Melting point:
180~181℃
Boiling point:
504.2±50.0 °C(Predicted)
Density 
1.395±0.06 g/cm3(Predicted)
storage temp. 
Amber Vial, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly, Heated)
pka
14.14±0.40(Predicted)
form 
Solid
color 
Off-White to Pale Yellow
Stability:
Light Sensitive
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Safety Information

Safety Statements 
24/25
HS Code 
29389090
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CORYNOLINE Usage And Synthesis

Description

The empirical formula of corynoline should read C21H21NO5

Uses

Corynoline is an isoquinoline alkaloid with reported pharmacological activity such as cell adhesion inhibition, sedation and liver protection.

Definition

ChEBI: A benzophenanthridine alkaloid that is chelidonine substituted by a methyl group at position 13. Isolated from the aerial parts of Corydalis incisa, it acts as an acetylcholinesterase inhibitor and also exhibits antineoplastic and hepatoprotec ive activity.

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