QUERCETIN-3-O-GLUCURONIDE Chemical Properties

Melting point:

193～195℃

Boiling point:

927.8±65.0 °C(Predicted)

Density 

1.96±0.1 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

2.76±0.70(Predicted)

color 

Yellow to Very Dark Yellow

Stability:

Very Hygroscopic

LogP

2.100 (est)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

QUERCETIN-3-O-GLUCURONIDE Usage And Synthesis

Description

Quercetin 3-O-glucuronide is a pharmacologically active flavonol glucuronide isolated from H. perforatum (St. John’s wort) that inhibits the α_2c adrenergic receptor (K_i = 4,060 nM in hα_2c preparations). Quercetin 3-O-glucuronide (0.6 mg/kg) reduced the time rats spent immobile in the forced swim test, suggesting antidepressant-like properties, when given either acutely or chronically. It also reduced open field stress-induced hyperthermia in mice (at 1.2 mg/kg).

Chemical Properties

Yellow Solid

Uses

Quercetin 3-O-β-D-Glucuronide is the major metabolite of Quercetin (Q509500).

Definition

ChEBI: Miquelianin is a quercetin O-glycoside that consists of quercetin attached to a beta-D-glucuronopyranosyl moiety at position 3 via a glycosidic linkage. Isolated from Salvia and Phaseolus vulgaris, it exhibits antioxidant and antidepressant activities. It has a role as a metabolite, an antioxidant and an antidepressant. It is a beta-D-glucosiduronic acid and a quercetin O-glycoside.

QUERCETIN-3-O-GLUCURONIDE(22688-79-5)Related Product Information

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