Milbemycin D Chemical Properties

Melting point:

186-188°

alpha 

D27 +107° (c = 0.25 in acetone)

Boiling point:

460.61°C (rough estimate)

Density 

1.0367 (rough estimate)

refractive index 

1.5300 (estimate)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

Chloroform (Slightly)

form 

Solid

pka

12.46±0.70(Predicted)

color 

White to Off-White

Stability:

Hygroscopic

Milbemycin D Usage And Synthesis

Uses

Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin D is a minor member of a group of analogues containing a 25-isopropyl substituent. Milbemycin D is a highly selective and potent nematocide and insecticide. Like the closely related avermectin, milbemycins are thought to act on chloride-gated ion channels.

Uses

Milbemycin D (Milbemycin EP Impurity C) is a macrocyclic lactones that can be used as a nematocide and insecticide.

Definition

ChEBI: Milbemycin D is a milbemycin originally isolated from Streptomyces hygroscopicus with formula C33H48O7 that has insecticidal and anthelmintic proerties. It has a role as an insecticide, an anthelminthic drug and a nematicide.

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