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2',5'-Dimethoxyacetophenone

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2',5'-Dimethoxyacetophenone Basic information

Product Name:
2',5'-Dimethoxyacetophenone
Synonyms:
  • Methyl 2,5-dimethoxyphenyl ketone
  • 2,5-Dimethoxy acetonphenone
  • 2',5'-Dimethoxyacetophenone,99%
  • 2',5'-Dimethoxyaceto
  • 1-(2,5-dimethoxyphenyl)-ethanon
  • Acetophenone, 2',5'-dimethoxy-
  • AKOS BBS-00004326
  • 1-(2,5-dimethoxyphenyl)-ethanone
CAS:
1201-38-3
MF:
C10H12O3
MW:
180.2
EINECS:
214-858-0
Product Categories:
  • Aromatic Acetophenones & Derivatives (substituted)
  • C10
  • Carbonyl Compounds
  • Ketones
  • Acetophenone series
  • 1201-38-3
Mol File:
1201-38-3.mol
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2',5'-Dimethoxyacetophenone Chemical Properties

Melting point:
18-20 °C(lit.)
Boiling point:
155-158 °C11 mm Hg(lit.)
Density 
1.139 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.5441(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform, Methanol (Slightly)
form 
Liquid
color 
Clear yellow to green-yellow
BRN 
2047423
InChIKey
FAXUIYJKGGUCBO-UHFFFAOYSA-N
LogP
2.125 (est)
CAS DataBase Reference
1201-38-3(CAS DataBase Reference)
NIST Chemistry Reference
Ethanone, 1-(2,5-dimethoxyphenyl)-(1201-38-3)
EPA Substance Registry System
Ethanone, 1-(2,5-dimethoxyphenyl)- (1201-38-3)
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Safety Information

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29145090

MSDS

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2',5'-Dimethoxyacetophenone Usage And Synthesis

Chemical Properties

clear yellow to green-yellow liquid

Uses

2'',5''-Dimethoxyacetophenone is a useful building block which has been used in the preparation of pyridine and thieno[2,3-b] pyridine derivatives as anticancer PIM-1 kinase inhibitors, and in the synthesis of anti-cancer and apoptosis-inducing agents.

Preparation

Obtained by reaction of dimethyl sulfate with quinacetophenone in the presence of 10% aqueous sodium hydroxide.

2',5'-Dimethoxyacetophenone Preparation Products And Raw materials

Preparation Products

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