4-Azido-L-homoalanine, (S)-2-Amino-4-azidobutanoic acid hydrochloride Chemical Properties

Melting point:

139°C

storage temp. 

-20°C

solubility 

Soluble in DMSO

form 

powder or crystals

color 

White to off-white

Water Solubility 

Soluble to 100 mM in water

Safety Information

HS Code 

2922498590

4-Azido-L-homoalanine, (S)-2-Amino-4-azidobutanoic acid hydrochloride Usage And Synthesis

Chemical Properties

White crystalline powder

Uses

L-Azidohomoalanine (AHA) is an amino acid analog of methionine that contains a very small modification, specifically an azido moiety. This compound can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or “click ” reaction between an azide and an alkyne or cyclooctyne. For example the azido-modified protein can be detected with either fluorescent alkyne or biotin alkyne. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and compatible with downstream LC-MS/MS and MALDI-MS analysis.

storage

Store at -20°C