Basic information Safety Supplier Related

alpha-Phthalimidopropiophenone

Basic information Safety Supplier Related

alpha-Phthalimidopropiophenone Basic information

Product Name:
alpha-Phthalimidopropiophenone
Synonyms:
  • 2-(1-Methyl-2-oxo-2-phenylethyl)-1H-isoindole-1,3(2H)-dione
  • A-PHTHALIMIDOPROPIOPHENONE
  • ALPHA-PHTHALIMIDOPROPIOPHENONE
  • a-Phtalimidopropiophnone
  • -Phthalimidopropiophenone
  • 2-PhthaliMido-1-phenylpropan-1-one
  • 2-(1-oxo-1-phenylpropan-2-yl)isoindole-1,3-dione
  • 1H-Isoindole-1,3(2H)-dione, 2-(1-methyl-2-oxo-2-phenylethyl)-
CAS:
19437-20-8
MF:
C17H13NO3
MW:
279.29
Mol File:
19437-20-8.mol
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alpha-Phthalimidopropiophenone Chemical Properties

Melting point:
87-88°C
Boiling point:
447.2±28.0 °C(Predicted)
Density 
1.304±0.06 g/cm3(Predicted)
solubility 
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml
form 
A crystalline solid
pka
-2.45±0.20(Predicted)
CAS DataBase Reference
19437-20-8(CAS DataBase Reference)
NIST Chemistry Reference
«ALPHA»-phthalimidopropiophenone(19437-20-8)
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Safety Information

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HazardClass 
IRRITANT
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alpha-Phthalimidopropiophenone Usage And Synthesis

Description

α-Phthalimidopropiophenone is a cathinone analog that has been identified in capsules being distributed by the illicit drug market. The substitution of the phthalimido moiety for the typical α-amino group may increase the stability of this cathinone in storage. Alternatively, similar nitrogen-protected propiophenones have been shown to be metabolized in vivo to produce cathinone, suggesting that this compound may act as a prodrug. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.

Uses

α-Phthalimidopropiophenone is a cathinone related phenylethylamine. The phthalamide addition at the nitrogen increases the stability of the cathinone in storage. Potential prodrug.

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