Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Analytical Chemistry >  Standard >  Analytical Standards >  Amodiaquin dihydrochloride dihydrate

Amodiaquin dihydrochloride dihydrate

Basic information Safety Supplier Related

Amodiaquin dihydrochloride dihydrate Basic information

Product Name:
Amodiaquin dihydrochloride dihydrate
Synonyms:
  • Amodiaquine hydrochloride USP24
  • AMODIAQUINE 2HCL DIHYDRATE
  • AMODIAQUINE DIHYDROCHLORIDE 2-HYDRATE
  • AMODIAQUIN DIHYDROCHLORIDE
  • amodiaquin dihydrochloride dihydrate
  • AMODIAQUINE DIHYDROCHLORIDE
  • AMODIAQUINE HCL
  • AMODIAQUIN HYDROCHLORIDE
CAS:
6398-98-7
MF:
C20H24Cl3N3O
MW:
428.78
EINECS:
642-210-0
Product Categories:
  • CAMOQUIN
Mol File:
6398-98-7.mol
More
Less

Amodiaquin dihydrochloride dihydrate Chemical Properties

RTECS 
GO7300100
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in DMSO or methanol
form 
neat
color 
White to Yellow to Orange
λmax
342nm(MeOH)(lit.)
Merck 
14,572
CAS DataBase Reference
6398-98-7(CAS DataBase Reference)
More
Less

Safety Information

WGK Germany 
3
HS Code 
2933492250

MSDS

More
Less

Amodiaquin dihydrochloride dihydrate Usage And Synthesis

Chemical Properties

Light yellow powder

Uses

An anti-malarial quinoline derivative that acts as an histamine N-methyltransferase inhibitor

Uses

antimalarial

brand name

Camoquin (Parke-Davis).

Biological Activity

Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase with estimated Ki of 18.6 nM. It is also used as an antimalarial and anti-inflammatory agent.

in vivo

In vivo administration of a small dose amodiaquine dramatically enhanced the effect of histamine on the gastric secretion in dogs. Amodiaquine prevents severe hepatic injury and high lethality in P. acnes-primed and LPS-induced hepatitis mice. Its treatment enhances the elevation of histamine in the liver of P. acnes-primed and LPS-induced hepatitis mice without accompanying tele-methyl histamine elevation.

Amodiaquin dihydrochloride dihydrateSupplier

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Email
sales@RHFChem.com
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Email
Sales-CN@TCIchemicals.com
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Email
master@sjzsdyn.com
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Email
info@chemlin.com.cn