Ranolazine-d3 Chemical Properties

Melting point:

113-1160C

storage temp. 

-20°C Freezer

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

color 

White

InChI

InChI=1S/C24H33N3O4/c1-18-7-6-8-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-10-5-4-9-21(22)30-3/h4-10,20,28H,11-17H2,1-3H3,(H,25,29)

InChIKey

XKLMZUWKNUAPSZ-UHFFFAOYSA-N

SMILES

c1cc(OCC(O)CN2CCN(CC(=O)Nc3c(C)cccc3C)CC2)c(OC)cc1

Ranolazine-d3 Usage And Synthesis

Chemical Properties

White Solid

Uses

Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Antianginal.

Uses

Ranolazine-d3 Dihydrochloride is the labeled analogue of Ranolazine Dihydrochloride (R122505), an anti-ischemic agent which modulates myocardial metabolism. Antianginal.

Uses

Ranolazine-d3 intended for use as an internal standard for the quantification of Ranolazine by GC- or LC-mass spectrometry.

Physiological effects

Ranolazine-d3 is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP). Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor. 

Ranolazine-d3(1054624-77-9)Related Product Information

• Ranolazine