4-METHOXYPHENETHYL ALCOHOL Chemical Properties

Melting point:

26-28 °C(lit.)

Boiling point:

334-336 °C(lit.)

Density 

1.058±0.06 g/cm3 (20 ºC 760 Torr)

refractive index 

1.536-1.538

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Soluble in DMSO, Methanol.

form 

Liquid After Melting

pka

15.00±0.16(Predicted)

color 

Clear light brown

FreezingPoint 

23.0 to 28.0 ℃

BRN 

2043563

LogP

1.393 (est)

CAS DataBase Reference

702-23-8(CAS DataBase Reference)

EPA Substance Registry System

4-Methoxybenzeneethanol (702-23-8)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

TSCA 

Yes

HS Code 

29062990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-METHOXYPHENETHYL ALCOHOL Usage And Synthesis

Chemical Properties

clear light brown liquid after melting

Uses

2-(4-Methoxyphenyl)ethanol is used as an internal standard in the fluorous biphasic catalysis reaction. It is used in the preparation of 4-(2-iodoethyl)phenol, by refluxing it with 47% hydriodic acid. It may be used in the preparation of (2R*,4R*)-1-n-butyl-2-methyl-4-(2-oxopyrrolidin-1-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline and (2R*,4S*)-1-n-butyl-2-methyl-4-(2-oxopyrrolidin-1-yl)-6-methoxy-1,2,3,4- tetrahydroquinoline. It is used for foods, perfumes, and cosmetics.

Uses

4-Methoxyphenethyl alcohol was used in the preparation of 4-(2-iodoethyl)phenol, by refluxing it with 47% hydriodic acid. It may be used in the preparation of (2R^*,4R^*)-1-n-butyl-2-methyl-4-(2-oxopyrrolidin-1-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline and (2R^*,4S^*)-1-n-butyl-2-methyl-4-(2-oxopyrrolidin-1-yl)-6-methoxy-1,2,3,4- tetrahydroquinoline.

Uses

4-Methoxyphenethyl alcohol has a flavor and aroma of fresh citrus juice and may be used for perfumes, foods, and cosmetics.

Synthesis Reference(s)

Journal of the American Chemical Society, 82, p. 3222, 1960 DOI: 10.1021/ja01497a062
Tetrahedron Letters, 33, p. 7465, 1992 DOI: 10.1016/S0040-4039(00)60796-7

General Description

(R)-1-(4-methoxyphenyl)ethanol {(R)-MOPE, 4-Methoxyphenethyl alcohol, 1-(4-methoxyphenyl)ethanol } is formed during the biocatalytic anti-Prelog enantioselective reduction of 4-methoxyacetophenone (MOAP) using immobilized Trigonopsis variabilis AS2.

4-METHOXYPHENETHYL ALCOHOL(702-23-8)Related Product Information

• METHYL 4-METHOXYPHENYLACETATE
• 3,4,5-Trimethoxyphenylacetic acid
• Methyl 3-(4-methoxyphenyl)oxirane-2-carboxylate
• Rotenone
• 4-Ethoxy-3-methoxyphenylacetic acid
• DL-4-HYDROXY-3-METHOXYMANDELIC ACID
• (+)-Bicuculline
• 2-(4-ETHOXYPHENYL)ETHANOL
• (3,4-Dimethoxyphenyl)acetic acid
• AFLATOXIN G1
• 4-N-BUTOXYPHENYLACETIC ACID
• 2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID
• 4-METHOXYMANDELIC ACID
• 2,3,4-TRIMETHOXYPHENYLACETIC ACID
• ANISOIN
• 1-(4-METHOXYPHENYL)-1-CYCLOHEXANECARBOXYLIC ACID
• 4-METHOXYPHENETHYL ALCOHOL
• 2,4,6-TRIMETHOXYPHENYLACETIC ACID