4-Methoxyphenyl isocyanate Chemical Properties

Melting point:

101 °C

Boiling point:

106-110 °C16 mm Hg(lit.)

Density 

1.151 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.548(lit.)

Flash point:

209 °F

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

soluble in Chloroform, Methanol

form 

Liquid

Specific Gravity

1.151

color 

Clear colorless

Sensitive 

Moisture Sensitive

BRN 

471920

CAS DataBase Reference

5416-93-3(CAS DataBase Reference)

NIST Chemistry Reference

P-methoxy phenyl isocyanate(5416-93-3)

EPA Substance Registry System

Benzene, 1-isocyanato-4-methoxy- (5416-93-3)

Safety Information

Hazard Codes 

C,Xi

Risk Statements 

20/21/22-34-36/37/38

Safety Statements 

26-36/37/39-45-37/39

RIDADR 

UN 2206 6.1/PG 3

WGK Germany 

3

F 

10-21

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29291090

MSDS

• Language:English Provider:4-Methoxyphenyl isocyanate
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Methoxyphenyl isocyanate Usage And Synthesis

Chemical Properties

clear colorless liquid

Uses

4-Methoxyphenyl isocyanate has been used in the preparation of:

• 6H-indolo[2,3-b]quinolines
• 1-[2-(2-furyl)-8-methyl-9-substituted-8H-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c] pyrimidin-5-yl]-3-(4-methoxyphenyl)urea

Synthesis Reference(s)

Tetrahedron Letters, 17, p. 2691, 1976 DOI: 10.1016/S0040-4039(00)77797-5

General Description

Cyclotrimerization of 4-methoxyphenyl isocyanate by CO₂-protected N-heterocyclic carbenes based on tetrahydropyrimidin-2-ylidenes has been reported.

4-Methoxyphenyl isocyanate(5416-93-3)Related Product Information

• Propyl isocyanate
• 3-Methoxybenzaldehyde
• Anisole
• o-Anisaldehyde
• 4-Methoxyphenylacetic acid
• p-Anisaldehyde
• m-Anisyl alcohol
• (Trifluoromethoxy)benzene
• (3-Methoxyphenyl)acetonitrile
• Methyl 4-formylbenzoate
• 2-Chloroethyl isocyanate
• 4-Fluorophenyl isocyanate
• 4-(HEPTYLOXY)PHENYL ISOCYANATE
• 3,4,5-TRIMETHOXYPHENYL ISOCYANATE
• 4-ETHOXYPHENYL ISOCYANATE
• 4-N-BUTOXYPHENYL ISOCYANATE
• 5-CHLORO-2,4-DIMETHOXYPHENYL ISOCYANATE
• ISOCYANATE