2-METHYL-2-PROPAN(OL-D) Chemical Properties

Melting point:

23-26 °C (lit.)

Boiling point:

83 °C (lit.)

Density 

0.786 g/mL at 25 °C

refractive index 

n20/D 1.3847(lit.)

Flash point:

52 °F

storage temp. 

Flammables area

solubility 

Acetone, Chloroform (Slightly), Methanol (Slightly)

form 

Solid

color 

Colourless Oil to White

explosive limit

2.3-8.0%(V)

InChI

1S/C4H10O/c1-4(2,3)5/h5H,1-3H3/i5D

InChIKey

DKGAVHZHDRPRBM-UICOGKGYSA-N

SMILES

[2H]OC(C)(C)C

CAS Number Unlabeled

75-65-0

Safety Information

Hazard Codes 

F,Xn

Risk Statements 

11-20-36/37

Safety Statements 

9-16-46

RIDADR 

UN 1120 3/PG 2

WGK Germany 

3

Storage Class

3 - Flammable liquids

Hazard Classifications

Acute Tox. 4 Inhalation
Eye Irrit. 2
Flam. Liq. 2
STOT SE 3

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

2-METHYL-2-PROPAN(OL-D) Usage And Synthesis

Chemical Properties

clear colorless liquid

Uses

Labelled Tert-butyl Alcohol is used as an organic solvent. Also it is used in the synthesis of proteosome inhibitors that are quite potent.

Uses

Tert-butyl Alcohol-OD is used as an organic solvent. Also it is used in the synthesis of proteosome inhibitors that are quite potent.

Synthesis

Deuterated tert-butanol can be used in organic synthesis, such as the preparation of ??,??-dideuterated alcohols, and an example of its application is as follows: in a 10 mL single-necked flask protected by nitrogen, 95.1 mg (0.50 mmol) of Compound 1d was added, 2.5 mL of tetrahydrofuran, 187.8 mg (2.50 mmol) of deuterated tert-butanol (t-BuOD), a 51.7 mg (2.25 mmol) sodium block, stirred for 5 min at 0 ??C. Raise to room temperature and burst the reaction with 3.0 M aqueous hydrochloric acid. Extracted by adding ether with saturated saline, the organic phase was dried, concentrated and separated by column chromatography to give 37.3 mg of the target compound in 54% yield.

2-METHYL-2-PROPAN(OL-D)(3972-25-6)Related Product Information

• TERT-BUTYL ACETATE-D12
• TERT-BUTANOL-D10
• CITRIC ACID-D8
• tert-Butanol
• Isopropanol-d
• 3-ETHYL-3-PENTANOL-OD
• MISOPROSTOL-D4
• 4-HYDROXY-4-METHYL-2-PENTANONE-D12
• 2-METHYL-2-PROPAN(OL-D)