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Quinine hydrochloride dihydrate

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Quinine hydrochloride dihydrate Basic information

Product Name:
Quinine hydrochloride dihydrate
Synonyms:
  • (R)(6-methoxy-4-quinolyl)(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol monohydrochloride dihydrate
  • Cinchonan-9-ol, 6-methoxy-, monohydrochloride, dihydrate, (8.alpha.,9R)-
  • QUININEHYDROCHLORIDE,DIHYDRATE,CRYSTAL
  • Quinine Monohy
  • Quinine HCl Dihydrate
  • (8α,9R)-6'-methoxy-cinchonan-9-ol,hydrochloride, hydrate (1:1:2)
  • (8α, 9R)-6′-Methoxycinchonan-9-ol monohydrochloride dihydrate
  • Quinine monohydrochloride dihydrate Vetec(TM) reagent grade, 88%
CAS:
6119-47-7
MF:
C20H27ClN2O3
MW:
378.9
EINECS:
612-097-2
Product Categories:
  • API
  • Alkaloids
  • Biochemistry
  • for Resolution of Acids
  • Optical Resolution
  • Quinoline Alkaloids
  • Synthetic Organic Chemistry
  • AlkaloidAntibiotics
  • Antibiotics A to
  • Antibiotics N-SAntibiotics
  • Spectrum of Activity
  • Alphabetical Listings
  • Flavors and Fragrances
  • Q-Z
  • chiral
  • Antiparasitic / Antiprotozoal / AnthelminthicVoltage-gated Ion Channels
  • Biochemicals Found in Plants
  • Monovalent Ion Channels
  • Nutrition Research
  • Potassium Channel Modulators
  • Other APIs
  • Inhibitors
  • 6119-47-7
Mol File:
6119-47-7.mol
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Quinine hydrochloride dihydrate Chemical Properties

Melting point:
115-116 °C (dec.)(lit.)
alpha 
[α]D20 -245~-255° (c=2, dil. HCl) (After Drying)
FEMA 
2976 | QUININE HYDROCHLORIDE
refractive index 
-250 ° (C=2, EtOH)
Flash point:
122 °C
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
H2O: soluble0.25/5g/mL, clear, colorless
form 
Crystalline Powder or Silky Needles
color 
White to off-white
PH
6.0 (10g/l, H2O, 20℃)
Odor
odorless
Odor Type
odorless
optical activity
[α]22/D 235°, c = 2 in 0.1 M HCl
Water Solubility 
Sparingly soluble in water.(0.26 g/L) (25°C),
Sensitive 
Light Sensitive
Merck 
14,8061
BRN 
6112655
InChIKey
MPQKYZPYCSTMEI-HPVDNOPASA-N
CAS DataBase Reference
6119-47-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
22-42/43-36/37/38-20/21/22
Safety Statements 
22-36/37-45-36/37/39-26-36
RIDADR 
1544
WGK Germany 
3
RTECS 
VA7700000
8
Hazard Note 
Irritant
HS Code 
29392000
Toxicity
LD50 orally in Rabbit: 620 mg/kg

MSDS

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Quinine hydrochloride dihydrate Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

Antiprotozoal (malaria).

Uses

Quinidine Hydrochloride Dihydrate is a salt of Quinidine (Q685000), a dextrorotatory stereoisomer of Quinine. Antiarrhythmic (class IA). Antimalarial.

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