3-Aminopyridine
3-Aminopyridine Basic information
- Product Name:
- 3-Aminopyridine
- Synonyms:
-
- 3-amino-pyridin
- 3-Aminopyridine ,98%
- 3-mydroxypiperidine
- 3-aMatopyridate
- NSC 15040
- Pyridine, 3-aMino- (8CI)
- AMINOPYRIDINE, 3-(RG)
- 462-08-0
- CAS:
- 462-08-8
- MF:
- C5H6N2
- MW:
- 94.11
- EINECS:
- 207-322-2
- Product Categories:
-
- Building Blocks
- C5
- Chemical Synthesis
- Heterocyclic Building Blocks
- Pyridines
- Pharmaceutical intermediates
- FINE Chemical & INTERMEDIATES
- Pyridine
- Organics
- Pyridine series
- Pyridines derivates
- Mol File:
- 462-08-8.mol
3-Aminopyridine Chemical Properties
- Melting point:
- 60-63 °C(lit.)
- Boiling point:
- 248 °C(lit.)
- Density
- 1.0308 (estimate)
- refractive index
- 1.5560 (estimate)
- Flash point:
- 124 °C
- storage temp.
- Poison room
- solubility
- >1000g/l
- form
- Liquid
- pka
- 6.04(at 25℃)
- color
- Clear colorless to yellow
- PH
- 10 (100g/l, H2O, 20℃)
- Water Solubility
- It is soluble in water as well as soluble in alcohol, benzene.
- Sensitive
- Air Sensitive & Hygroscopic
- Merck
- 14,473
- BRN
- 105692
- InChIKey
- CUYKNJBYIJFRCU-UHFFFAOYSA-N
- CAS DataBase Reference
- 462-08-8(CAS DataBase Reference)
- NIST Chemistry Reference
- 3-Pyridinamine(462-08-8)
- EPA Substance Registry System
- 3-Aminopyridine (462-08-8)
Safety Information
- Hazard Codes
- T,Xi
- Risk Statements
- 23/24/25-33-36/37/38-25
- Safety Statements
- 36/37/39-45-37/39-28B-26
- RIDADR
- UN 2671 6.1/PG 2
- WGK Germany
- 3
- RTECS
- US1650000
- F
- 3-8-9-23
- Hazard Note
- Toxic/Irritant
- TSCA
- T
- HazardClass
- 6.1
- PackingGroup
- II
- HS Code
- 29333999
- Toxicity
- LD50 ipr-mus: 28 mg/kg JMCMAR 8,296,65
MSDS
- Language:English Provider:3-Pyridinamine
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
3-Aminopyridine Usage And Synthesis
Chemical Properties
white to light yellow crystal powder
Uses
3-Aminopyridine is a monosubstituted pyridine that shows convulsive effects on cortical Neurons. 3-Aminopyridine is used in the synthesis of of organic ligand 3-Pyridylnicotinamide. 3-Aminopyridine al ong with other aminopyridines have been shown to reversibly block voltage-dependent potassium channels,
Uses
manufacture of pharmaceuticals and dyes.
Uses
3-Aminopyrodine is also used as an intermediate for agrochemicals, pharmaceuticals and colorants. These are involved in photosensitizer chemistry, luminescent materials, metal complex chemistry and liquid crystal. Aminopyridine is used as a monomer for polymerization. It is also used in the Production of cationic dyes and Apa amoxicillin sodium raw materials.
Synthesis Reference(s)
Tetrahedron Letters, 39, p. 1313, 1998 DOI: 10.1016/S0040-4039(97)10877-2
The Journal of Organic Chemistry, 57, p. 5254, 1992 DOI: 10.1021/jo00045a047
Safety Profile
Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NOx,.
Purification Methods
It crystallises from *benzene, CHCl3/pet ether (b 60-70o), or *benzene/pet ether (4:1). [Beilstein 22/9 V 3.]
3-Aminopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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3-Aminopyridine(462-08-8)Related Product Information
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