3-Aminopyridine
3-Aminopyridine Basic information
- Product Name:
- 3-Aminopyridine
- Synonyms:
-
- 3-amino-pyridin
- 3-Aminopyridine ,98%
- 3-mydroxypiperidine
- 3-aMatopyridate
- NSC 15040
- Pyridine, 3-aMino- (8CI)
- AMINOPYRIDINE, 3-(RG)
- 462-08-0
- CAS:
- 462-08-8
- MF:
- C5H6N2
- MW:
- 94.11
- EINECS:
- 207-322-2
- Product Categories:
-
- Building Blocks
- C5
- Chemical Synthesis
- Heterocyclic Building Blocks
- Pyridines
- Pharmaceutical intermediates
- FINE Chemical & INTERMEDIATES
- Pyridine
- Organics
- Pyridine series
- Pyridines derivates
- Mol File:
- 462-08-8.mol
3-Aminopyridine Chemical Properties
- Melting point:
- 60-63 °C(lit.)
- Boiling point:
- 248 °C(lit.)
- Density
- 1.0308 (estimate)
- refractive index
- 1.5560 (estimate)
- Flash point:
- 124 °C
- storage temp.
- Poison room
- solubility
- >1000g/l
- form
- Liquid
- pka
- 6.04(at 25℃)
- color
- Clear colorless to yellow
- PH
- 10 (100g/l, H2O, 20℃)
- Water Solubility
- It is soluble in water as well as soluble in alcohol, benzene.
- Sensitive
- Air Sensitive & Hygroscopic
- Merck
- 14,473
- BRN
- 105692
- InChIKey
- CUYKNJBYIJFRCU-UHFFFAOYSA-N
- LogP
- 0.110
- CAS DataBase Reference
- 462-08-8(CAS DataBase Reference)
- NIST Chemistry Reference
- 3-Pyridinamine(462-08-8)
- EPA Substance Registry System
- 3-Aminopyridine (462-08-8)
Safety Information
- Hazard Codes
- T,Xi
- Risk Statements
- 23/24/25-33-36/37/38-25
- Safety Statements
- 36/37/39-45-37/39-28B-26
- RIDADR
- UN 2671 6.1/PG 2
- WGK Germany
- 3
- RTECS
- US1650000
- F
- 3-8-9-23
- Hazard Note
- Toxic/Irritant
- TSCA
- T
- HazardClass
- 6.1
- PackingGroup
- II
- HS Code
- 29333999
- Toxicity
- LD50 ipr-mus: 28 mg/kg JMCMAR 8,296,65
MSDS
- Language:English Provider:3-Pyridinamine
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
3-Aminopyridine Usage And Synthesis
Chemical Properties
white to light yellow crystal powder
Uses
3-Aminopyridine is a monosubstituted pyridine that shows convulsive effects on cortical Neurons. 3-Aminopyridine is used in the synthesis of of organic ligand 3-Pyridylnicotinamide. 3-Aminopyridine al ong with other aminopyridines have been shown to reversibly block voltage-dependent potassium channels,
Uses
3-Aminopyrodine is also used as an intermediate for agrochemicals, pharmaceuticals and colorants. These are involved in photosensitizer chemistry, luminescent materials, metal complex chemistry and liquid crystal. Aminopyridine is used as a monomer for polymerization. It is also used in the Production of cationic dyes and Apa amoxicillin sodium raw materials.
Uses
manufacture of pharmaceuticals and dyes.
Synthesis Reference(s)
Tetrahedron Letters, 39, p. 1313, 1998 DOI: 10.1016/S0040-4039(97)10877-2
The Journal of Organic Chemistry, 57, p. 5254, 1992 DOI: 10.1021/jo00045a047
Safety Profile
Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NOx,.
Purification Methods
It crystallises from *benzene, CHCl3/pet ether (b 60-70o), or *benzene/pet ether (4:1). [Beilstein 22/9 V 3.]
3-Aminopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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3-Aminopyridine(462-08-8)Related Product Information
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- 2-CHLORO-3,5-DINITROPYRIDINE
- 3,4-Diaminopyridine
- 2-CHLORO-3-NITROPYRIDINE
- 2-Amino-5-nitropyridine
- 2-(2-AMINOETHYLAMINO)-5-NITROPYRIDINE
- 2-Methoxy-5-nitropyridine
- 2-methoxy-5-aminopyridine
- 5-Amino-2-chloropyridine
- 3-Amino-2-Chloropyridine 2-Chloro-3-Aminopyridine
- (3alpha)-3-chloro-Cholest-4-ene
- 4-Dimethylaminopyridine
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- 4-Aminopyridine;4-AP; Pyridin-4-amine,4-Aminopyridine (RTC is agent for this item in Europe)
- 2-Aminopyridine