Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Heterocyclic compound >  Pyridine compound >  Aminopyridine >  3-Aminopyridine

3-Aminopyridine

Basic information Safety Supplier Related

3-Aminopyridine Basic information

Product Name:
3-Aminopyridine
Synonyms:
  • 3-amino-pyridin
  • 3-Aminopyridine ,98%
  • 3-mydroxypiperidine
  • 3-aMatopyridate
  • NSC 15040
  • Pyridine, 3-aMino- (8CI)
  • AMINOPYRIDINE, 3-(RG)
  • 462-08-0
CAS:
462-08-8
MF:
C5H6N2
MW:
94.11
EINECS:
207-322-2
Product Categories:
  • Building Blocks
  • C5
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Pyridines
  • Pharmaceutical intermediates
  • FINE Chemical & INTERMEDIATES
  • Pyridine
  • Organics
  • Pyridine series
  • Pyridines derivates
Mol File:
462-08-8.mol
More
Less

3-Aminopyridine Chemical Properties

Melting point:
60-63 °C(lit.)
Boiling point:
248 °C(lit.)
Density 
1.0308 (estimate)
refractive index 
1.5560 (estimate)
Flash point:
124 °C
storage temp. 
Poison room
solubility 
>1000g/l
pka
6.04(at 25℃)
form 
Liquid
color 
Clear colorless to yellow
PH
10 (100g/l, H2O, 20℃)
Water Solubility 
It is soluble in water as well as soluble in alcohol, benzene.
Sensitive 
Air Sensitive & Hygroscopic
Merck 
14,473
BRN 
105692
InChIKey
CUYKNJBYIJFRCU-UHFFFAOYSA-N
CAS DataBase Reference
462-08-8(CAS DataBase Reference)
NIST Chemistry Reference
3-Pyridinamine(462-08-8)
EPA Substance Registry System
3-Aminopyridine (462-08-8)
More
Less

Safety Information

Hazard Codes 
T,Xi
Risk Statements 
23/24/25-33-36/37/38-25
Safety Statements 
36/37/39-45-37/39-28B-26
RIDADR 
UN 2671 6.1/PG 2
WGK Germany 
3
RTECS 
US1650000
3-8-9-23
Hazard Note 
Toxic/Irritant
TSCA 
T
HazardClass 
6.1
PackingGroup 
II
HS Code 
29333999
Toxicity
LD50 ipr-mus: 28 mg/kg JMCMAR 8,296,65

MSDS

More
Less

3-Aminopyridine Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

3-Aminopyridine is a monosubstituted pyridine that shows convulsive effects on cortical Neurons. 3-Aminopyridine is used in the synthesis of of organic ligand 3-Pyridylnicotinamide. 3-Aminopyridine al ong with other aminopyridines have been shown to reversibly block voltage-dependent potassium channels,

Uses

manufacture of pharmaceuticals and dyes.

Uses

3-Aminopyrodine is also used as an intermediate for agrochemicals, pharmaceuticals and colorants. These are involved in photosensitizer chemistry, luminescent materials, metal complex chemistry and liquid crystal. Aminopyridine is used as a monomer for polymerization. It is also used in the Production of cationic dyes and Apa amoxicillin sodium raw materials.

Synthesis Reference(s)

Tetrahedron Letters, 39, p. 1313, 1998 DOI: 10.1016/S0040-4039(97)10877-2
The Journal of Organic Chemistry, 57, p. 5254, 1992 DOI: 10.1021/jo00045a047

Safety Profile

Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NOx,.

Purification Methods

It crystallises from *benzene, CHCl3/pet ether (b 60-70o), or *benzene/pet ether (4:1). [Beilstein 22/9 V 3.]

3-AminopyridineSupplier

Alfa Aesar Gold
Tel
400-610-6006; 021-67582000
Email
saleschina@alfa-asia.com
Shijiazhuang Jinchi Chemical Co., Ltd. Gold
Tel
15176121996
Email
15176121996@163.com
Hangzhou Cyanochem Co., Ltd. Gold
Email
info@cyanochem.com
Yancheng Huahong Chemical Co., Ltd. Gold
Email
sales@huahongchem.com
Jiaxing Nova Chemical Co., Ltd. Gold
Tel
021-20921617-
Email
2240425080@qq.com