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3-Aminopyridine

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3-Aminopyridine Basic information

Product Name:
3-Aminopyridine
Synonyms:
  • 3-amino-pyridin
  • 3-Aminopyridine ,98%
  • 3-mydroxypiperidine
  • 3-aMatopyridate
  • NSC 15040
  • Pyridine, 3-aMino- (8CI)
  • AMINOPYRIDINE, 3-(RG)
  • 462-08-0
CAS:
462-08-8
MF:
C5H6N2
MW:
94.11
EINECS:
207-322-2
Product Categories:
  • Building Blocks
  • C5
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Pyridines
  • Pharmaceutical intermediates
  • Pyridine series
  • Pyridines derivates
  • FINE Chemical & INTERMEDIATES
  • Pyridine
  • Organics
Mol File:
462-08-8.mol
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3-Aminopyridine Chemical Properties

Melting point:
60-63 °C(lit.)
Boiling point:
248 °C(lit.)
Density 
1.0308 (estimate)
refractive index 
1.5560 (estimate)
Flash point:
124 °C
storage temp. 
Poison room
solubility 
>1000g/l
pka
6.04(at 25℃)
form 
Liquid
color 
Clear colorless to yellow
PH
10 (100g/l, H2O, 20℃)
Water Solubility 
It is soluble in water as well as soluble in alcohol, benzene.
Sensitive 
Air Sensitive & Hygroscopic
Merck 
14,473
BRN 
105692
InChIKey
CUYKNJBYIJFRCU-UHFFFAOYSA-N
CAS DataBase Reference
462-08-8(CAS DataBase Reference)
NIST Chemistry Reference
3-Pyridinamine(462-08-8)
EPA Substance Registry System
3-Aminopyridine (462-08-8)
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Safety Information

Hazard Codes 
T,Xi
Risk Statements 
23/24/25-33-36/37/38-25
Safety Statements 
36/37/39-45-37/39-28B-26
RIDADR 
UN 2671 6.1/PG 2
WGK Germany 
3
RTECS 
US1650000
3-8-9-23
Hazard Note 
Toxic/Irritant
TSCA 
T
HazardClass 
6.1
PackingGroup 
II
HS Code 
29333999
Toxicity
LD50 ipr-mus: 28 mg/kg JMCMAR 8,296,65

MSDS

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3-Aminopyridine Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

3-Aminopyridine is a monosubstituted pyridine that shows convulsive effects on cortical Neurons. 3-Aminopyridine is used in the synthesis of of organic ligand 3-Pyridylnicotinamide. 3-Aminopyridine al ong with other aminopyridines have been shown to reversibly block voltage-dependent potassium channels,

Uses

manufacture of pharmaceuticals and dyes.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 4, p. 45, 1963
The Journal of Organic Chemistry, 57, p. 5254, 1992
Tetrahedron Letters, 39, p. 1313, 1998 DOI: 10.1016/S0040-4039(97)10877-2

Safety Profile

Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NOx,.

Purification Methods

It crystallises from *benzene, CHCl3/pet ether (b 60-70o), or *benzene/pet ether (4:1). [Beilstein 22/9 V 3.]

3-AminopyridineSupplier

Alfa Aesar Gold
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Shijiazhuang Jinchi Chemical Co., Ltd. Gold
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15176121996
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JinJinLe Chemical Gold
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10106090
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Hangzhou Cyanochem Co., Ltd. Gold
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Yancheng Huahong Chemical Co., Ltd. Gold
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