L-Lysine hydrochloride Chemical Properties

Melting point:

263 °C (dec.)(lit.)

alpha 

21 º (c=8, 6N HCl)

Density 

1.28 g/cm3 (20℃)

vapor pressure 

<1 Pa (20 °C)

FEMA 

3847 | L-LYSINE

storage temp. 

2-8°C

solubility 

H₂O: 100 mg/mL

form 

powder

color 

White to Off-white

PH

5.5-6.0 (100g/l, H2O, 20℃)

Odor

odorless

optical activity

[α]20/D +20.5±0.5°, c = 5% in 5 M HCl

Water Solubility 

65 g/100 mL (20 ºC)

λmax

λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.1

Merck 

14,5636

BRN 

3563889

Stability:

Stable. Incompatible with strong oxidizing agents.

LogP

-1.036 (est)

CAS DataBase Reference

657-27-2(CAS DataBase Reference)

EPA Substance Registry System

Lysine hydrochloride (657-27-2)

Safety Information

Hazard Codes 

WGK Germany 

2

HS Code 

2922410000

MSDS

• Language:English Provider:L(+)-2,6-Diaminocaproic acid hydrochloride
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

L-Lysine hydrochloride Usage And Synthesis

Synthesis

L-Lysine hydrochloride can be synthesisied by microbial fermentation to give crude L-Lysine , and then purified and synthesized by crystallization in hydrochloric acid.

Description

A white or nearly white, practically odorless, free-flowing, crys talline powder. It is freely soluble in water, but is almost insoluble in alcohol and in ether. It melts at about 260°C with decomposition.

Chemical Properties

White crystalline powder

Uses

amino acid, nutrient

Uses

L-(+)-Lysine Monohydrochloride

Uses

L-Lysine monohydrochloride is widely used as nutritional supplements in food and beverage industries. It can also be used in animal feed as source of L-Lysine.? L-Lysine Monohydrochloride can be used in a wide variety of industries including: food production, beverage, pharmaceutical, agriculture/animal feed, and various other industries.

Definition

ChEBI: The hydrochloride salt of L-lysine

Biochem/physiol Actions

L-lysine is an essential amino acid in animals and humans. L-Lysine is necessary for protein synthesis in the body and proper growth. L-lysine lowers the cholesterol level by producing carnitine. L-lysine aids in calcium, zinc and iron absorption. Athletes take L-lysine as a supplement for lean mass building and for proper muscle and bone health. L-lysine competes with arginine during viral replication and reduces herpes simplex virus infection. L-lysine supplementation reduces chronic anxiety in human. Lysine reduces viscosity of serum albumin solution for injections.

Safety Profile

iWdly toxic by ingestion. When heated to decomposition it emits very toxic fumes of HCl and NOx.

Purification Methods

Likely impurities are arginine, D-lysine, 2,6-diaminoheptanedioic acid and glutamic acid. Crystallise the monohydrochloride from water at pH 4-6 by adding 4 volumes of EtOH. At above 60% relative humidity it forms a dihydrate. [Birhbaum et al. J Biol Chem 194 455, 468 1952, Kearley & Ingersoll J Am Chem Soc 73 5783 1951, Beilstein 4 IV 2717.]

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