L-Lysine hydrochloride Chemical Properties

Melting point:

263 °C (dec.)(lit.)

alpha 

21 º (c=8, 6N HCl)

Density 

1.28 g/cm3 (20℃)

vapor pressure 

<1 Pa (20 °C)

FEMA 

3847 | L-LYSINE

storage temp. 

2-8°C

solubility 

H₂O: 100 mg/mL

form 

powder

color 

White to Off-white

Odor

odorless

PH

5.5-6.0 (100g/l, H2O, 20℃)

optical activity

[α]20/D +20.5±0.5°, c = 5% in 5 M HCl

Water Solubility 

65 g/100 mL (20 ºC)

λmax

λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.1

Merck 

14,5636

BRN 

3563889

Stability:

Stable. Incompatible with strong oxidizing agents.

LogP

-1.036 (est)

CAS DataBase Reference

657-27-2(CAS DataBase Reference)

EPA Substance Registry System

Lysine hydrochloride (657-27-2)

Safety Information

Hazard Codes 

WGK Germany 

2

HS Code 

2922410000

MSDS

• Language:English Provider:L(+)-2,6-Diaminocaproic acid hydrochloride
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

L-Lysine hydrochloride Usage And Synthesis

Synthesis

L-Lysine hydrochloride can be synthesisied by microbial fermentation to give crude L-Lysine , and then purified and synthesized by crystallization in hydrochloric acid.

Description

L-Lysine hydrochloride is a white or nearly white, practically odorless, free-flowing, crys talline powder. It is freely soluble in water, but is almost insoluble in alcohol and in ether. It melts at about 260°C with decomposition.

Chemical Properties

White crystalline powder

Uses

L-Lysine hydrochloride is widely used as nutritional supplements in food and beverage industries. It can also be used in animal feed as source of L-Lysine. It can be used in a wide variety of industries including: food production, beverage, pharmaceutical, agriculture/animal feed, and various other industries.

Definition

ChEBI: The hydrochloride salt of L-lysine

Biochem/physiol Actions

L-lysine is an essential amino acid in animals and humans. L-Lysine is necessary for protein synthesis in the body and proper growth. L-lysine lowers the cholesterol level by producing carnitine. L-lysine aids in calcium, zinc and iron absorption. Athletes take L-lysine as a supplement for lean mass building and for proper muscle and bone health. L-lysine competes with arginine during viral replication and reduces herpes simplex virus infection. L-lysine supplementation reduces chronic anxiety in human. Lysine reduces viscosity of serum albumin solution for injections.

Side effects

L-Lysine hydrochloride may cause side effects such as stomach pain and diarrhea.

Safety Profile

L-Lysine hydrochloride is hazardous by inhalation. When heated to decomposition it emits very toxic fumes of HCl and NOx.

Purification Methods

Likely impurities are arginine, D-lysine, 2,6-diaminoheptanedioic acid and glutamic acid. Crystallise the monohydrochloride from water at pH 4-6 by adding 4 volumes of EtOH. At above 60% relative humidity it forms a dihydrate. [Birhbaum et al. J Biol Chem 194 455, 468 1952, Kearley & Ingersoll J Am Chem Soc 73 5783 1951, Beilstein 4 IV 2717.]

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