IB-MECA Chemical Properties

Density 

1.98±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

hot ethanol: >10 mg/mL

pka

12.72±0.70(Predicted)

form 

solid

color 

white

InChIKey

HUJXGQILHAUCCV-MOROJQBDSA-N

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

IB-MECA Usage And Synthesis

Uses

IB-MECA has been used for intraocular pressure and corneal thickness measurements in rabbits.

Definition

ChEBI: A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by N-ethylcarboxamido and one of the hydrogens of the exocyclic amino function is substituted by a 3-iodobenzyl group.

Biological Activity

Potent and selective A 3 adenosine receptor agonist (K i values are 1.1, 54 and 56 nM for A 3 , A 1 and A 2A receptors respectively). Cardioprotective, reduces infarct size upon reperfusion in rats.

Biochem/physiol Actions

Selective A3 adenosine receptor agonist.

storage

Desiccate at +4°C

IB-MECA(152918-18-8)Related Product Information

• CHLORO-IB-MECA
• (S)-(+)-Tetrahydrofurfurylamine
• 1-[6-[[(4-AMINO-3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-1-DEOXY-N-METHYL-BETA-D-RIBOFURANURONAMIDE
• adenosine 5'-carboxamide
• (S)-(-)-TETRAHYDROFURAN-2-CARBOXYLIC ACID AMIDE
• 5'-AMINOADENOSINE
• 2-CL-IB-MECA,Cl-IB-MECA, 2-Chloro-N6-(3-iodobenzyl)-adenosine-5μ-N-methyluronamide
• 5'-N-METHYLCARBOXAMIDOADENOSINE
• IB-MECA