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3-FLUORO-4-(TRIFLUOROMETHYL)BENZOIC ACID

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3-FLUORO-4-(TRIFLUOROMETHYL)BENZOIC ACID Basic information

Product Name:
3-FLUORO-4-(TRIFLUOROMETHYL)BENZOIC ACID
Synonyms:
  • alpha,alpha,alpha,3-Tetrafluoro-p-toluic Acid
  • 4-Carboxy-2-fluorobenzotrifluoride, alpha,alpha,alpha,3-Tetrafluoro-p-toluic acid
  • 3-Fluoro-4-(trifluoroMethyl)benzoic aicd
  • 3-Fuoro-4-trifluoromethylbenzoic acid
  • Benzoic acid, 3-fluoro-4-(trifluoromethyl)-
  • RARECHEM AL BO 0852
  • 3-FLUORO-4-(TRIFLUOROMETHYL)BENZOIC ACID
  • 3-Fluoro-4-(trifluoromethyl)benzoic acid, 97+%
CAS:
115754-21-7
MF:
C8H4F4O2
MW:
208.11
EINECS:
624-783-9
Product Categories:
  • C8
  • Carbonyl Compounds
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • Benzoic acid
  • Carboxylic Acids
  • Fluorine series
Mol File:
115754-21-7.mol
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3-FLUORO-4-(TRIFLUOROMETHYL)BENZOIC ACID Chemical Properties

Melting point:
174-179 °C (lit.)
Boiling point:
251℃
Density 
1.489
Flash point:
106℃
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
3.35±0.10(Predicted)
form 
Solid
color 
White to Off-White
InChIKey
HRIHSNPFVGMAKX-UHFFFAOYSA-N
CAS DataBase Reference
115754-21-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29163990

MSDS

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3-FLUORO-4-(TRIFLUOROMETHYL)BENZOIC ACID Usage And Synthesis

Chemical Properties

White to off-white crystalline powder

Uses

3-Fluoro-4-(trifluoromethyl)benzoic acid serves as a crucial building block in the synthesis of potassium channel openers used for the treatment of epilepsy. The potassium channel openers are synthesised by condensation reactions involving 3-fluoro-4-(trifluoromethyl)benzoic acid and aminopyridine.

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