15(S)-15-METHYL PROSTAGLANDIN E1 Chemical Properties

Boiling point:

534.9±50.0 °C(Predicted)

Density 

1.118±0.06 g/cm3(Predicted)

solubility 

DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1)

pka

4.77±0.10(Predicted)

15(S)-15-METHYL PROSTAGLANDIN E1 Usage And Synthesis

Description

15(S)-15-methyl Prostaglandin E₁ (15(S)-15-methyl PGE₁) is a metabolically stable synthetic analog of PGE₁ . In sharp contrast to the bronchodilatory effects of PGE₁, 15(S)-15-methyl PGE₁ is a weak constrictor of human respiratory tract smooth muscle.¹

Definition

ChEBI: 15-Methyl-15S-Prostaglandin E1 is a prostanoid.

References

1. Karim, S.M.M., Adaikan, P.G., and Kottegoda, S.R. Prostaglandins and human respiratory tract smooth muscle: Structure activity relationship Adv. Prostaglandin Thromboxane Res. 7,969-980(1980).

15(S)-15-METHYL PROSTAGLANDIN E1(35700-26-6)Related Product Information

• 15(S)-15-Methyl prostaglandin
• 1,11ALPHA,15S-TRIHYDROXY-PROST-13E-EN-9-ONE
• CIS-2,5-DIMETHYL-3-HEXENE
• Doxaprost
• DELTA 10 TRANS HEPTADECENOIC ACID
• 11-DEOXY PROSTAGLANDIN E1
• Prostaglandin E1
• 15(S)-15-METHYL PROSTAGLANDIN E1