DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE
DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE Basic information
- Product Name:
- DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE
- Synonyms:
-
- (+-)-4-hydroxy-3-methoxy-alpha-((methylamino)methyl)benzenemethanolhydrochlo
- 3-methoxy-adrenalinhydrochloride
- 4-hydroxy-3-methoxy-alpha-((methylamino)methyl)-benzenemethanohydrochlorid
- alpha-((methylamino)methyl)-vanillylalcohohydrochloride
- 4-HYDROXY-3-METHOXY-ALPHA-[METHYLAMINOMETHYL]BENZENE-METHANOL HYDROCHLORIDE
- 4-HYDROXY-3-METHOXY-ALPHA-(METHYLAMINOMETHYL)BENZYL ALCOHOL HYDROCHLORIDE
- METANEPHRINE (HCL)
- METANEPHRINE HYDROCHLORIDE
- CAS:
- 881-95-8
- MF:
- C10H16ClNO3
- MW:
- 233.69
- EINECS:
- 212-922-2
- Product Categories:
-
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Standards - 13C & 2H for GC-Mass Spectrometry
- Pharmaceuticals
- Mol File:
- 881-95-8.mol
DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE Chemical Properties
- Melting point:
- 180-182?C
- Density
- 1.320 g/cm3
- storage temp.
- 2-8°C
- solubility
- H2O: soluble
- form
- powder
- color
- white to off-white
- Stability:
- Hygroscopic
MSDS
- Language:English Provider:SigmaAldrich
DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE Usage And Synthesis
Chemical Properties
Off-White to Pale Yellow Solid
Uses
A metabolite of Epinephrine (E588585). A naturraly occurring derivative of Epinephrine, found in urine and in certain tissues.
Biochem/physiol Actions
Metanephrine is an endogenous metabolite of ephinephrine, formed by catechol-O-methyl transferase activity. It is best known as a biomarker for cancers, as levels of free metanephrine are used to diagnose pheochromocytoma. Metanephrine was previously thought to be biologically inactive, but it is a more potent agonist at Trace amine associated receptor TAAR1 than either epinephrine or norepinephrine. Trace amine associated receptors (TAARs) are recently discovered GPCRs that are activated by endogenous trace amines (tyramine, tryptamine, synephrine, octopamine, β-phenylethylamine), which are chemically similar to monoaminergic neurotransmitters (epinephrine, norepinephrine, dopamine). Trace amines and TAARs are expressed in brain and are implicated in modulation of monoaminergic neurotransmission.
DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDESupplier
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DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE(881-95-8)Related Product Information
- Methoxyammonium chloride
- Norepinephrine
- L(-)-Epinephrine
- NOSCAPINE HYDROCHLORIDE
- Dipivefrin hydrochloride
- (+)-B-HYDRASTINE HCL
- DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE
- BICUCULLINE METHYLCHLORIDE (-), [METHYL-3H]
- PHOMOPSIN A
- DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE
- METANEPHRINE HYDROCHLORIDE [N-METHYL-3H]
- (-)-BICUCULLINE METHOCHLORIDE
- BICUCULLINE METHYLCHLORIDE (-), [METHYL-14C]
- (-)-BICUCULLINE METHCHLORIDE, 1(S),9(R)
- NOSCAPINE HYDROCHLORIDE HYDRATE
- TIMTEC-BB SBB006457
- LABOTEST-BB LT00847526
- SALOR-INT L123331-1EA