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ChemicalBook >  Product Catalog >  Organic Chemistry >  Heterocyclic Compounds >  (S,S)-(-)-2,2'-ISOPROPYLIDENEBIS(4-TERT-BUTYL-2-OXAZOLINE)

(S,S)-(-)-2,2'-ISOPROPYLIDENEBIS(4-TERT-BUTYL-2-OXAZOLINE)

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(S,S)-(-)-2,2'-ISOPROPYLIDENEBIS(4-TERT-BUTYL-2-OXAZOLINE) Basic information

Product Name:
(S,S)-(-)-2,2'-ISOPROPYLIDENEBIS(4-TERT-BUTYL-2-OXAZOLINE)
Synonyms:
  • 2,2'-ISOPROPYLIDENEBIS[(4S)-4-TERT-BUTYL-2-OXAZOLINE]
  • (S,S)-(-)-2,2'-(DIMETHYLMETHYLENE)BIS(4-TERT-BUTYL-2-OXAZOLINE)
  • (S,S)-2,2'-ISOPROPYLIDENE-BIS(4-TERT-BUTYL-2-OXAZOLINE)
  • (S,S)-(-)-2,2-BIS(4-TERT-BUTYL-2-OXAZOLIN-2-YL)PROPANE
  • 2,2-isopropylidenebis((4S)-4-tert-butyl-2-oxazol
  • Isopropylidenebisbutyloxazoline
  • (S,S)-(-)-2,2-Isopropylidenebis(4-Tert-Butyl-2-Oxazolin
  • (S,S)-2,2''-ISOPROPYLIDENE-BIS(4-TERT- BUTYL-2-OXAZOLINE) 98+%
CAS:
131833-93-7
MF:
C17H30N2O2
MW:
294.43
Product Categories:
  • organic building block
  • BOX series
  • Chiral Nitrogen
  • Asymmetric Synthesis
  • Synthetic Organic Chemistry
  • Amino Alcohols & Deriv.
  • CHIRAL CHEMICALS
  • Chiral Reagents
Mol File:
131833-93-7.mol
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(S,S)-(-)-2,2'-ISOPROPYLIDENEBIS(4-TERT-BUTYL-2-OXAZOLINE) Chemical Properties

Melting point:
89-91 °C(lit.)
Boiling point:
350.4±25.0 °C(Predicted)
Density 
1.04±0.1 g/cm3(Predicted)
refractive index 
-118 ° (C=1, CHCl3)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
insol H2O; sol all common organic solvents
pka
5.69±0.70(Predicted)
form 
Crystalline Powder
color 
White to light yellow
optical activity
[α]20/D 120°, c = 5 in chloroform
InChI
InChI=1S/C17H30N2O2/c1-15(2,3)11-9-20-13(18-11)17(7,8)14-19-12(10-21-14)16(4,5)6/h11-12H,9-10H2,1-8H3/t11-,12-/m1/s1
InChIKey
DPMGLJUMNRDNMX-VXGBXAGGSA-N
SMILES
C(C1=N[C@@H](C(C)(C)C)CO1)(C1=N[C@@H](C(C)(C)C)CO1)(C)C
CAS DataBase Reference
131833-93-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29349990

MSDS

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(S,S)-(-)-2,2'-ISOPROPYLIDENEBIS(4-TERT-BUTYL-2-OXAZOLINE) Usage And Synthesis

Uses

Chiral catalyst for asymmetric synthesis. C2 symmetric ligand for enantioselective catalysis. Easily forms bidentate coordination complexes due to the strong affinity of the oxazoline nitrogen for various metals.

Preparation

(S,S)-(-)-2,2'-ISOPROPYLIDENEBIS(4-TERT-BUTYL-2-OXAZOLINE) is readily prepared from chiral β-amino alcohols using standard methods for the synthesis of 2-oxazolines.

storage

(S,S)-(-)-2,2'-ISOPROPYLIDENEBIS(4-TERT-BUTYL-2-OXAZOLINE) is stable at ambient temperature; for longer periods, storage at -20 °C is recommended.

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