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5,6-DIHYDRO-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE

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5,6-DIHYDRO-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE Basic information

Product Name:
5,6-DIHYDRO-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE
Synonyms:
  • 5,6-DIHYDRO-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE
  • (±)-Gerberin aglycone
  • 4-Hydroxy-5,6-dihydro-6-methyl-2H-pyran-2-one
  • 4-hydroxy-2-methyl-2,3-dihydropyran-6-one
  • 2H-Pyran-2-one, 5,6-dihydro-4-hydroxy-6-methyl-
  • 5,6-DIHYDRO-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE ISO 9001:2015 REACH
  • 4-Hydroxy-6-methyl-5,6-dihydro-2h-pyran-2-one
CAS:
33177-29-6
MF:
C6H8O3
MW:
128.13
EINECS:
200-001-8
Product Categories:
  • API intermediates
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyrans
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
Mol File:
33177-29-6.mol
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5,6-DIHYDRO-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE Chemical Properties

Melting point:
126-128 °C (lit.)
Boiling point:
280.3±40.0 °C(Predicted)
Density 
1.252±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
4.50±1.00(Predicted)
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Safety Information

WGK Germany 
3

MSDS

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5,6-DIHYDRO-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE Usage And Synthesis

Uses

5,6-Dihydro-4-hydroxy-6-methyl-2H-pyran-2-one was used in the synthesis of spiro-γ/δ-dilactone as a mixture of diastereomers.

Uses

5,6-Dihydro-4-hydroxy-6-methyl-2H-pyran-2-one can be used in the synthesis of spiroheterocycles with fused heterosystems; preparation of insecticidal heterolignans and cyclization of aminoanilino lactones on diazotization.

Synthesis Reference(s)

Chemistry Letters, 4, p. 161, 1975
Journal of Heterocyclic Chemistry, 15, p. 1153, 1978 DOI: 10.1002/jhet.5570150717

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