1-METHYLADENOSINE Chemical Properties

Melting point:

>217°C (dec.)

Boiling point:

655.4±65.0 °C(Predicted)

Density 

1.88±0.1 g/cm3(Predicted)

storage temp. 

−20°C

solubility 

DMSO (Slightly), Water (Slightly, Sonicated)

form 

Solid

pka

13.24±0.70(Predicted)

color 

White to Off-White

PH

8.8

λmax

258 (pH 2)；258 (pH 7)；259，260～265 (pH 13)

Stability:

Hygroscopic, Light Sensitive

Safety Information

Safety Statements 

24/25

HS Code 

29389090

1-METHYLADENOSINE Usage And Synthesis

Description

1-Methyladenosine is a modified nucleoside generated by the processing of tRNA by methyltransferases. The urinary excretion of 1-methyladenosine is elevated in several forms of cancer, supporting its use as a biomarker in early detection. It can also be monitored in serum. Urinary levels of 1-methyladenosine also increase during active rheumatoid arthritis.

Chemical Properties

White to off-white crystalline powder

Uses

1-Methyl Adenosine is a modified adenosine molecule created through the processing of tRNA by methyltransferases. The presence seen to be elevated in the urinary excretion of cancer patients. Thus it may be an early diagnosis biomarker.

Definition

ChEBI: A methyladenosine carrying a methyl substituent at position 1.

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