2-MERCAPTO-L-HISTIDINE Chemical Properties

Melting point:

320-325°C

Boiling point:

376.3±52.0 °C(Predicted)

Density 

1.52±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,2-8°C

solubility 

Aqueous Acid (Slightly)

form 

Solid

pka

pK1:1.84(＋1);pK2:8.47(0);pK3:11.4(SH) (25°C)

color 

Off-White

2-MERCAPTO-L-HISTIDINE Usage And Synthesis

Chemical Properties

Colourless Crystals

Uses

An intermediate in the formation of L-egothioneine, a natural amino acid ubiquitously present in cells and tissues of most plants and mammalian species. In humans, L-ergothioneine is found in red blood cells, liver, kidney, brain, seminal fluid, and cataract-free lenses at concentrations ranging from 100 uM to 2 mM. L-ergothioneine is exclusively biosynthesized in fungi and mycobacteria. Hence, humans assimilate it through dietary intake.L-ergothioneine has been proven to act as an antioxidant in vivo and to afford protection from g and UV radiation as well as from singlet oxygen in vivo. Recently, it has been shown that L-ergothioneine protects isolated perfused heart against the deleterious effect of post-ischemic reperfusion.The intermediate, 2-mercaptohistine has been used for the

2-MERCAPTO-L-HISTIDINE(2002-22-4)Related Product Information

• BARIUM THIOSULFATE
• L-Histidine
• D-2-Thiolhistidine
• thiolhistidine betain
• 2-MERCAPTO-L-HISTIDINE METHYL ESTER
• L-2-Thiolhistidine
• 2-MERCAPTOIMIDAZOLE
• 2-CHLOROMETHYL-5-(4-CHLOROPHENYL)-1,3,4-THIADIAZOLE
• L-(+)-Ergothioneine
• 2-MERCAPTO-L-HISTIDINE