Benzylmagnesium chloride Chemical Properties

Boiling point:

182 °C(Press: 16 Torr)

Density 

1.031 g/mL at 25 °C

Flash point:

1 °F

storage temp. 

water-free area

form 

Liquid

color 

Brown to purple

Water Solubility 

Severe reaction

Sensitive 

Air & Moisture Sensitive

BRN 

878506

InChIKey

NRAFPLGJPPJUNB-UHFFFAOYSA-M

CAS DataBase Reference

6921-34-2(CAS DataBase Reference)

EPA Substance Registry System

Magnesium, chloro(phenylmethyl)- (6921-34-2)

Safety Information

Hazard Codes 

F+,C,Xi,F

Risk Statements 

12-14-34-66-67-36/37-19-11-14/15-40-37-17-22

Safety Statements 

16-29-33-7/8-45-43-36/37/39-26-6A-43B

RIDADR 

UN 2924 3/PG 2

WGK Germany 

1

F 

1-3-10

TSCA 

Yes

HazardClass 

4.3

PackingGroup 

II

HS Code 

29319090

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

Benzylmagnesium chloride Usage And Synthesis

Chemical Properties

Light gray to dark amber-grey slurry or solution

Uses

Benzyl magnesium chloride is used as a Grignard reagent in greener solvent, 2-methyltetrahydrofuran (2-MeTHF). It is also used as organic chemical synthesis intermediate.

Uses

Benzylmagnesium chloride (Grignard reagent) can be used as an alkylating reagent:

• For alkylating quinolyl-functionalized Cp?chromium(III) complexes which are used as precursors for the preparation of active olefin polymerization catalysts.
• In the synthesis of 2,3-disubstituted benzopyran-4-ones, 6-chloro-8-methylpurine derivative, and phenylalanine derivatives.

Application

Benzylmagnesium chloride (Grignard reagent) can be used as an alkylating reagent:
For alkylating quinolyl-functionalized Cp?chromium(III) complexes which are used as precursors for the preparation of active olefin polymerization catalysts.
In the synthesis of 2,3-disubstituted benzopyran-4-ones, 6-chloro-8-methylpurine derivative, and phenylalanine derivatives.

General Description

This product has been enhanced for energy efficiency.

Research

Grignard reagents are organometallic compounds discovered by a French chemist, Victor Grignard in 1900. These compounds can be obtained as a formula “RMgX” by the reaction of halogenated hydrocarbons with magnesium metal in anhydrous solvents such as diethyl ether,1) and have been widely used in organic synthesis.
Grignard reagents are usually used as solutions, and they are typically grayish white ~ light brown clear solutions. They generally exist in an equilibrium between alkyl magnesium halides (RMgX) and dialkyl magnesium (R2Mg), which form equilibrium mixtures with complicated compositions (called “Schlenk equilibrium”).2) Furthermore, some of these species may cause precipitation due to their lower solubility. However, there is no problem in actual use.
In the case of precipitation being formed:
Please use it after gently shaking the bottle to fully disperse the suspension (If the amount of precipitation is very small, you can use the top clear layer of the suspension). Especially in cold conditions such as in winter, a large amount of precipitate may frequently form. In this case, please use it after crushing the solid with a dried glass stick. Alternatively, you can also use it the following. The bottle is put into a plastic bag and soaking in a water bath with warming at 40 degree C to dissolve the solid. Please be careful of volatilization of the organic solvent when the bottle is unsealing.

Precautions

It reacts violently with water. Air & moisture sensitive. Incompatible with oxidizing agents and bases.

Benzylmagnesium chloride(6921-34-2)Related Product Information

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