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H-GLY-GLY-PHE-OH

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H-GLY-GLY-PHE-OH Basic information

Product Name:
H-GLY-GLY-PHE-OH
Synonyms:
  • (S)-2-[(N-Glycylglycyl)amino]-3-phenylpropionic acid
  • Gly-Gly-L-Phe-OH
  • Gly-Gly-Phe-OH
  • (S)-2-(2-(2-AMinoacetaMido)acetaMido)-3-phenylpropanoic acid
  • GLY-GLY-PHE
  • GLYCYL-GLYCYL-L-PHENYLALANINE
  • H-GLY-GLY-PHE-OH
  • (2S)-2-[2-(2-aminoacetamido)acetamido]-3-phenylpropanoic acid
CAS:
6234-26-0
MF:
C13H17N3O4
MW:
279.29
Product Categories:
  • ADCs Linkers
Mol File:
6234-26-0.mol
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H-GLY-GLY-PHE-OH Chemical Properties

Melting point:
228-230 °C (decomp)
Boiling point:
647.1±55.0 °C(Predicted)
Density 
1.296±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
pka
3.47±0.10(Predicted)
form 
Solid
InChI
InChI=1S/C13H17N3O4/c14-7-11(17)15-8-12(18)16-10(13(19)20)6-9-4-2-1-3-5-9/h1-5,10H,6-8,14H2,(H,15,17)(H,16,18)(H,19,20)/t10-/m0/s1
InChIKey
KAJAOGBVWCYGHZ-JTQLQIEISA-N
SMILES
C(O)(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CN
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H-GLY-GLY-PHE-OH Usage And Synthesis

Chemical Properties

White powder

Uses

H-Gly-Gly-Phe-OH is a tripeptide linker that may be used in the creation of antibody drug conjugates (ADCs). The N-terminal of the glycine tripeptide is free to perform a variety of reactions such as couplings with carboxylic acids or NHS esters.

Definition

ChEBI: A tripeptide composed of glycine, glycine and L-phenylalanine residues joined in sequence.

H-GLY-GLY-PHE-OHSupplier

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