Basic information Safety Supplier Related

DIISOPROPANOLNITROSAMINE

Basic information Safety Supplier Related

DIISOPROPANOLNITROSAMINE Basic information

Product Name:
DIISOPROPANOLNITROSAMINE
Synonyms:
  • 1,1’-(nitrosoimino)bis-2-propano
  • 1,1’-nitrosoiminodi-2-propano
  • 2,2’-bishydroxypropylnitrosamine
  • 2,2’-dihydroxy-di-n-propylnitrosoamine
  • 2,2’-dihydroxy-n-nitroso-dipropylamin
  • bhp
  • di(2-hydroxypropyl)nitrosamine
  • n,n-di-(2-hydroxypropyl)nitrosamine
CAS:
53609-64-6
MF:
C6H14N2O3
MW:
162.19
Product Categories:
  • Aliphatics
  • Nitric Oxide Reagents
Mol File:
53609-64-6.mol
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DIISOPROPANOLNITROSAMINE Chemical Properties

Boiling point:
288.88°C (rough estimate)
Density 
1.2266 (rough estimate)
refractive index 
1.4650 (estimate)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
viscous liquid
pka
13.90±0.20(Predicted)
color 
yellow
EPA Substance Registry System
N-Nitrosodiisopropanolamine (53609-64-6)
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Safety Information

Hazard Codes 
T
Risk Statements 
45
Safety Statements 
53-23-36/37/39-45
WGK Germany 
3
RTECS 
JL9650000

MSDS

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DIISOPROPANOLNITROSAMINE Usage And Synthesis

Chemical Properties

Thick Yellow Oil

Uses

It shows carcinogenicity in the duct cells.

Definition

ChEBI: A nitrosamine that is dipropylamine in which the hydrogen attached to the nitrogen has been replaced by a nitroso group. It is a genotoxic carcinogen, targeting the lung, liver, thyroid, and kidney.

Safety Profile

Suspected carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Moderately toxic by subcutaneous route. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITROSAMINES.

in vivo

N-Bis(2-hydroxypropyl)nitrosamine causes the tumors to develop in the lung, liver, and thyroid of rats at a dose of 100 ppm, in the lung, liver thyroid, esophagus, kidney, and urinary bladder of rats at a dose of 500 ppm, and in the lung, liver thyroid, esophagus, kidney, and urinary bladder of rats at both doses[1]. Bisphenol A (BPA) enhances the susceptibility to thyroid carcinoma stimulated by N-Bis(2-hydroxypropyl)nitrosamine (DHPN; 2800 mg/kg) in rats[2].

DIISOPROPANOLNITROSAMINESupplier

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