ChemicalBook > Product Catalog > API > Digestive system drugs > Gastrointestinal antispasmodic drugs > Adiphenine hydrochloride
Adiphenine hydrochloride
Adiphenine hydrochloride Basic information
- Product Name:
- Adiphenine hydrochloride
- Synonyms:
-
- 2-(Diethylamino)ethyl a-phenylbenzeneacetate hydrochloride
- Disodium (6E)-4-amino-3-(4-nitrophenyl)diazenyl-5-oxo-6-(phenylhydrazinylidene)naphthalene-2,7-disulfonate
- Oil Black S
- Orient Water Black R 455
- Spasnil
- Spasmolytin
- 2,2-diphenylacetic acid 2-diethylaminoethyl ester hydrochloride
- 2-diethylaminoethyl 2,2-diphenylacetate hydrochloride
- CAS:
- 50-42-0
- MF:
- C20H25NO2.ClH
- MW:
- 347.88
- EINECS:
- 200-036-9
- Product Categories:
-
- ETHYOL
- Mol File:
- 50-42-0.mol
More
Less
Adiphenine hydrochloride Chemical Properties
- Melting point:
- 113-114°
- Density
- 1.0555 (rough estimate)
- refractive index
- 1.5400 (estimate)
- storage temp.
- Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Very Slightly)
- form
- Solid
- color
- White
- Merck
- 14,161
- InChI
- InChI=1S/C20H25NO2.ClH/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-13-9-6-10-14-18;/h5-14,19H,3-4,15-16H2,1-2H3;1H
- InChIKey
- LKPINBXAWIMZCG-UHFFFAOYSA-N
- SMILES
- C(C(=O)OCCN(CC)CC)(C1=CC=CC=C1)C1=CC=CC=C1.Cl
- CAS DataBase Reference
- 50-42-0(CAS DataBase Reference)
More
Less
MSDS
- Language:English Provider:Diphenylacetic acid 2-(diethylamino)ethyl ester hydrochloride
- Language:English Provider:SigmaAldrich
More
Less
Adiphenine hydrochloride Usage And Synthesis
Originator
Adiphenine hydrochloride,Spectrum Chemicals and Laboratory Products, Inc.
Uses
radioprotectant
Uses
Adiphenine hydrochloride is an anticholinergic. Adiphenine hydrochloride is used as an antispasmodic.
Manufacturing Process
10.6 parts of α,α-diphenylacetic acid are treated with thionyl chloride and the diphenylacetylchloride thus produced is caused to react with 5.9 parts of diethylaminoethanol at 120°C. The α,α-diphenylacetic acid, 2- (diethylamino)ethanol ester hydrochloride thus produced is crystallized from ethyl acetate; it melts at 113-114°C.
Therapeutic Function
Anticholinergic, Spasmolytic, Smooth muscle relaxant
in vivo
Adiphenine (i.p.) prevents the hindleg tonic-extensor component of maximal electroshock seizures (MES), with an ED50 of 62 mg/kg in mice[3].
Adiphenine hydrochlorideSupplier
Jinan Shengqi Pharmaceutical Co., Ltd Gold
- Tel
- 15610111696
- xgc01@orgachem.com
J & K SCIENTIFIC LTD.
- Tel
- 18210857532; 18210857532
- jkinfo@jkchemical.com
TCI (Shanghai) Development Co., Ltd.
- Tel
- 021-67121386
- Sales-CN@TCIchemicals.com
Shanghai Longsheng chemical Co.,Ltd.
- Tel
- 021-58099652-8005 13585536065
- bin.wu@shlschem.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
More
Less
Adiphenine hydrochloride(50-42-0)Related Product Information
- 4-Hydroxyphenylacetic acid
- ISOXADIFEN-ETHYL
- Aminoacetonitrile hydrochloride
- Ethyl acetate
- Diphenhydramine Hydrochloride
- Methyl acrylate
- Difenidol
- D-Glucosamine hydrochloride
- Tris(trimethylsilyl)phosphate
- 1-AdaMantanethylaMine
- Ethylparaben
- 2-Hydroxyphenylacetic acid
- Azasetron hydrochloride
- Topotecan hydrochloride
- Amitriptyline hydrochloride
- Doxorubicin hydrochloride
- Difenidol hydrochloride
- Aminoguanidine hydrochloride