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Herbacetin 7-rhamnoside

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Herbacetin 7-rhamnoside Basic information

Product Name:
Herbacetin 7-rhamnoside
Synonyms:
  • 7-(α-L-Rhamnopyranosyloxy)-3,5,8-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
  • Herbacetin 7-rhamnoside
  • Rhodionin
  • Herbacetin7-O--L-rhaMnopyranoside
  • Herbacetin 7-O-α-rhamnopyranoside
  • SynonymsHerbacetin7-O-α-L-rhamnopyranoside
  • 4H-1-Benzopyran-4-one, 7-[(6-deoxy-α-L-mannopyranosyl)oxy]-3,5,8-trihydroxy-2-(4-hydroxyphenyl)-
  • 3,5,8-trihydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one
CAS:
85571-15-9
MF:
C21H20O11
MW:
448.38
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • E-0922
Mol File:
85571-15-9.mol
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Herbacetin 7-rhamnoside Chemical Properties

Melting point:
234-237 °C
Boiling point:
802.9±65.0 °C(Predicted)
Density 
1.737±0.06 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
powder
pka
6.67±0.40(Predicted)
color 
Yellow
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Herbacetin 7-rhamnoside Usage And Synthesis

Chemical Properties

Orange powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the dried rhizomes of Rhodiola rosea.

Uses

Rhodionin has an effect of nourishing and strengthening, clearing away heat and moistening the lungs.

Biological Activity

Rhodionin, isolated from the roots of Rhodiola crenulata, is a specific, noncompetitive cytochrome P450 2D6 inhibitor with IC50 of 0.761 μM and Ki of 0.769 μM. It has potent DPPH free radical scavenging activity with IC50 of 19.49 μM.

target

IC50: 0.761 μM (cytochrome P450 2D6); 57.50-2.43 μg/mL (AChE); 19.49 μM (DPPH free radical scavenging)

Herbacetin 7-rhamnosideSupplier

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