Basic information Safety Supplier Related

CAY10568

Basic information Safety Supplier Related

CAY10568 Basic information

Product Name:
CAY10568
Synonyms:
  • TRIMETHYL ((PHENYLCARBAMOYL)METHYL) AMMONIUM IODIDE
  • (2-anilino-2-oxoethyl)-trimethylazanium:iodide
  • CAY10568
  • CAY10568,CAY-10568
CAS:
22913-17-3
MW:
0
Mol File:
22913-17-3.mol
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CAY10568 Chemical Properties

storage temp. 
Store at -20°C
solubility 
DMF: 5 mg/ml; DMSO: 3 mg/ml; PBS (pH 7.2): 0.5 mg/ml
form 
A crystalline solid
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CAY10568 Usage And Synthesis

Description

Most local anesthetics act by abolishing voltage gated sodium channel currents indiscriminately in all populations of neurons. Selective analgesia through TRPV1-mediated entry of a cationic lidocaine derivative, QX314, was recently reported.1 CAY10568 is a physically smaller, less hydrophobic version of QX314 designed to be even more permeable to TRPV1 ion channel when activated by agonists such as capsaicin and N-oleoyl dopamine. CAY10568 when given in combination with suitable TRPV1 agonists should produce selective blockade of the pain response while leaving motor, touch, and proprioception intact.

References

1. Binshtok, A.M., Bean, B.P., and Woolf, C.J. Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers Nature 449,607-610(2007).

CAY10568Supplier

Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Shanghai Haohong Scientific Co., Ltd.
Tel
400-400-8210725
Email
malulu@leyan.com
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com