Basic information Safety Supplier Related

1-(TERT-BUTOXYCARBONYL)-3-(1-PIPERAZINYL)AZETIDINE

Basic information Safety Supplier Related

1-(TERT-BUTOXYCARBONYL)-3-(1-PIPERAZINYL)AZETIDINE Basic information

Product Name:
1-(TERT-BUTOXYCARBONYL)-3-(1-PIPERAZINYL)AZETIDINE
Synonyms:
  • 1-(TERT-BUTOXYCARBONYL)-3-(1-PIPERAZINYL)AZETIDINE
  • 3-(Piperazin-1-yl)azetidine-1-carboxylic acid tert-butyl ester
  • tert-Butyl 3-(1-piperazinyl)-1-azetidinecarboxylate
  • 1-Boc-3-(1-piperazinyl)azetidine 2HCl
  • 1-N-Boc-3-(1-piperazine)azetidine
  • tert-butyl 3-(piperazin-1-yl)azetidine-1-carboxylate
  • 1-Azetidinecarboxylic acid, 3-(1-piperazinyl)-, 1,1-dimethylethyl ester
  • 1,1-Dimethylethyl 3-(1-piperazinyl)-1-azetidinecarboxylate
CAS:
178311-48-3
MF:
C12H23N3O2
MW:
241.33
Mol File:
178311-48-3.mol
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1-(TERT-BUTOXYCARBONYL)-3-(1-PIPERAZINYL)AZETIDINE Chemical Properties

Boiling point:
337.3±37.0 °C(Predicted)
Density 
1.115
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
9.12±0.10(Predicted)
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1-(TERT-BUTOXYCARBONYL)-3-(1-PIPERAZINYL)AZETIDINE Usage And Synthesis

Uses

tert-Butyl 3-(piperazin-1-yl)azetidine-1-carboxylate dihydrochloride is used as a reactant in the preparation of allele-specific inhibitors that inactivate mutant KRAS G12C by a trapping mechanism.

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