Basic information Safety Supplier Related

CYFLUMETOFEN

Basic information Safety Supplier Related

CYFLUMETOFEN Basic information

Product Name:
CYFLUMETOFEN
Synonyms:
  • CYFLUMETOFEN
  • 2-Methoxyethyl (rs)-2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-(alpha,alpha,alpha-trifluoro-o-tolyl)propionate
  • Cyflumetofen [iso]
  • alpha-Cyano-alpha-[4-(1,1-dimethylethyl)phenyl]-beta-oxo-2-(trifluoromethyl)benzenepropanoic acid 2-methoxyethyl ester
  • 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate
  • CYFLUMETOFEN CYFLUMETOFEN
  • 2-Methoxyethyl (RS)-2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-(α,α,α-trifluoro-o-tolyl)propionate
  • 2-Methoxyethyl 2-cyano-2-[4-(2-methyl-2-propanyl)phenyl]-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate
CAS:
400882-07-7
MF:
C24H24F3NO4
MW:
447.45
Mol File:
400882-07-7.mol
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CYFLUMETOFEN Chemical Properties

Boiling point:
533.8±50.0 °C(Predicted)
Density 
1.214
solubility 
DMSO (Slightly), Methanol (Slightly)
BRN 
11332768
EPA Substance Registry System
Benzenepropanoic acid, .alpha.-cyano-.alpha.-[4-(1,1-dimethylethyl)phenyl]-.beta.-oxo-2-(trifluoromethyl)-, 2-methoxyethyl ester (400882-07-7)
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Safety Information

Hazard Codes 
Xn,N
Risk Statements 
20-43-50
Safety Statements 
36/37-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
2
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CYFLUMETOFEN Usage And Synthesis

Chemical Properties

Cyflumetofen is an acracide and insecticide. It has a low aqueous solubility and is non-toxic. It tends not to be persistent in the environment. Whilst its toxicity to honeybees is low it t has a moderate to high toxicity to most other biodiversity. Its oral mammalian toxicity is low.

Uses

Cyflumetofen is a novel acaricide that only affects spider mites.

Definition

ChEBI: 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate is a nitrile that is acetonitrile in which the methyl hydrogens have been replaced by o-trifluoromethylbenzoyl, p-tert-butylphenyl, and (2-methoxyethoxy)carbonyl groups. It is a nitrile, a beta-ketoester, a member of (trifluoromethyl)benzenes and a 2-methoxyethyl ester.

Biological Activity

It has been shown to inhibit the activity of detoxification enzymes and mitochondrial membrane potential, which may be responsible for its toxicity in insects. Cyflumetofen also causes a synergic effect with other chemicals, such as pesticides, by increasing their toxicity to insects.

Mechanism of action

cyflumetofen inhibited mitochondria complex II in mites. In addition, the de-esterified form (AB-1) of cyflumetofen inhibited mitochondria complex II at extremely low concentrations. AB-1 was also detected as the main metabolite in mites. The mode of action of cyflumetofen is to inhibit mitochondria complex II by affecting its action site after being metabolised to AB-1. However, inhibition by cyflumetofen and AB-1 in other organisms was very weak. Selectivity for other organisms has contributed to differences in action site activities.

CYFLUMETOFENSupplier

Hubei Zhengxingyuan Fine Chemical Co., Ltd. Gold
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Beijing Isomersyn Technology CO;LTD
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UHN Shanghai Research & Development Co., Ltd.
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Cantotech Chemicals, Ltd.
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Shanghai Run-Biotech Co., Ltd.
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021-57171705 13817537615
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sales@run-biotech.com