Basic information Safety Supplier Related

(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid

Basic information Safety Supplier Related

(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid Basic information

Product Name:
(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid
Synonyms:
  • (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid
  • 3-Azetidinepropanoic acid, 1-(4-fluorophenyl)-2-oxo-4-[4-(phenylMethoxy)phenyl]-, (3R,4S)-
  • 1-(4-fluorophenyl)-2-oxo-4-[4-(phenylMethoxy)phenyl]-, (3R,4S)-3-Azetidinepropanoic acid
  • 3-((2S,3R)-2-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-4-oxoazetidin-3-yl)propanoic acid
  • Ezetimibe Impurity 13
  • 3-[(3R,4S)-1-(4-fluorophenyl)-2-oxo-4-(4-phenylmethoxyphenyl)azetidin-3-yl]propanoic acid
  • (3R,4S)-3-Azetidinepropanoic acid,1-(4-fluorophenyl)-2-oxo-4[4(phenylmethoxy)phenyl]-methyl ester
  • (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-a...
CAS:
204589-82-2
MF:
C25H22FNO4
MW:
419.44
EINECS:
1308068-626-2
Mol File:
204589-82-2.mol
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(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid Chemical Properties

Boiling point:
687.4±55.0 °C(Predicted)
Density 
1.292
storage temp. 
2-8°C
pka
4.53±0.10(Predicted)
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(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid Usage And Synthesis

Uses

(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic Acid is a reagent for the synthesis of antihypercholesterolemia drug Ezetimibe. Also a reagent for the preparation of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4-hydroxyphenyl)-2-azetidinone (SCH 58235) designed as inhibitor of cholesterol absorption.

(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acidSupplier

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