STIGMASTANOL Chemical Properties

Melting point:

144°C

Boiling point:

474.98°C (rough estimate)

Density 

0.9444 (rough estimate)

refractive index 

1.5000 (estimate)

storage temp. 

Store at -20°C

solubility 

Chloroform: Slightly Soluble

form 

A solid

pka

15.14±0.70(Predicted)

color 

White to off-white

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

24-26-36

WGK Germany 

-

MSDS

• Language:English Provider:SigmaAldrich

STIGMASTANOL Usage And Synthesis

Uses

Stigmastanol is used in food product formulations for prevention and treatment of hypercholesterolemia, hypertension and inflammation disorders in humans

Definition

ChEBI: A 3-hydroxy steroid that is 5alpha-stigmastane which is substituted at the 3beta position by a hydroxy group.

Biological Activity

Plant stanols are structurally similar to cholesterol, hence it reduces the plasma level of LDL cholesterol. Sitostanol is known to possess hypolipidemic and antiatherogenic effects.', 'Sitostanol decreases cholesterol absorption. Its ratio with cholesterol is implicated in non-alcoholic fatty liver disease (NAFLD). The ratio also correlates with liver steatosis and inflammation. Sitostanol induces interferon γ production and T-helper response in peripheral blood mononuclear cells (PBMC) in asthma patients. It is a hypocholestremic agent as it decreases the micellar solubility and absorption of cholesterol.', 'Sitostanol lowers the intestinal absorption of cholesterol and serum cholesterol.

STIGMASTANOL(83-45-4)Related Product Information

• beta-Sitosterol
• BETA-SITOSTEROL
• stigmastanol glucoside
• STIGMASTANOL
• STIGMASTANOL = BETA-SITOSTANOL = FUCOSTANOL
• STIGMASTANOL(P)
• STIGMASTANOL MALTOSIDE
• 5β-Stigmastanol