5-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine Chemical Properties

Density 

2.09

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

pka

3.99±0.30(Predicted)

form 

solid

Appearance

White to off-white Solid

InChI

InChI=1S/C6H5BrN4/c7-4-2-1-3-5-9-6(8)10-11(4)5/h1-3H,(H2,8,10)

InChIKey

TVGFHUIJNZRKFW-UHFFFAOYSA-N

SMILES

C12=NC(N)=NN1C(Br)=CC=C2

Safety Information

Hazard Codes 

T

Risk Statements 

25

Safety Statements 

45

RIDADR 

UN 2811 6.1 / PGIII

WGK Germany 

3

HS Code 

2933998090

5-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine Usage And Synthesis

Uses

5-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine is an important organic reagent that can be used as an organic intermediate for the synthesis of many organic compounds, such as N- (5-bromo- [1,2,4] triazolo [1,5-a] pyridin-2-yl) cyclopropylacetamide.

Synthesis

2-Amino-6-bromopyridine could be used to synthesize 5-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 17, p. 5014 - 5021
[2] Patent: WO2009/155565, 2009, A1. Location in patent: Page/Page column 92-93
[3] Patent: WO2012/970, 2012, A1. Location in patent: Page/Page column 30-31
[4] Journal of Medicinal Chemistry, 2017, vol. 60, # 13, p. 5663 - 5672
[5] Patent: WO2010/141796, 2010, A2. Location in patent: Page/Page column 182

5-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine(1010120-55-4)Related Product Information

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