DEXTROSE Chemical Properties

Melting point:

153-156 °C(lit.)

Boiling point:

232.96°C (rough estimate)

Density 

1.544g/cm3

refractive index 

n20/D 1.362

storage temp. 

Sealed in dry,Room Temperature

solubility 

H₂O: 1 M at 20 °C, clear, colorless

form 

solution

pka

12.12±0.70(Predicted)

color 

White

PH

5.0-8.0 (25℃)

Odor

odorless

optical activity

[α]20/D +52°, c = 10 in H2O

Water Solubility 

450.5g/L(25 ºC)

λmax

λ: 260 nm Amax: 0.04
λ: 280 nm Amax: 0.04

BRN 

1281608

LogP

-1.880 (est)

CAS DataBase Reference

492-62-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

WGK Germany 

3

RTECS 

LZ6600000

F 

3

HS Code 

17023000

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

DEXTROSE Usage And Synthesis

Chemical Properties

white, odorless, fine crystalline powder

Uses

α-D-Glucose is used:

• As a reducing agent in the preparation superparamagnetic ferrous oxide (Fe₃O₄) nanoparticles and silver nanocrystals.
• As an additive for the formation of isoporous polystyrene-block-poly(4-vinylpyridine) (PS-b-P4VP) diblock copolymer membranes.
• For glycosylation of cell-penetrating poly(disulfide)s (CPDs) with improved solubility to achieve multifunctional cellular uptake.
• As a precursor in the synthesis of metal/carbon nanohybrids under hydrothermal conditions.

Uses

D-(+)-Glucose is a common natural sugar involved in processes such as energy production, glycosylation, and formation of glycans that provide structure to cells. Glucose is involved in a detrimentatl process in cells called glycation. Glucose is used as a supplement for cell culture and in numerous cellular processes and molecular biology applications.

Definition

ChEBI: D-Glucopyranose having alpha-configuration at the anomeric centre.

Purification Methods

Recrystallise -D-glucose slowly from aqueous 80% EtOH, then dry it over P2O5 in vacuo. Alternatively, crystallise it from water at 55o, then dry it for 6hours in a vacuum oven between 60-70o/2mm. Its solubilities are: H2O (~50%), EtOH (1.7%). [Hendricks et al. J Am Chem Soc 56 99 1934, Beilstein 1 IV 4302.] [For equilibrium forms see Angyal Adv Carbohydr Chem 42 15 1984, Angyal & Pickles Aust J Chem 25 1711 1972.]

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