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(S)-(-)-Tolvaptan

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(S)-(-)-Tolvaptan Basic information

Product Name:
(S)-(-)-Tolvaptan
Synonyms:
  • (S)-(-)-Tolvaptan
  • Tolvaptan (S)-Isomer
  • N-[4-[(5S)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide
  • Tolvaptan Impurity S-Isomer
  • Benzamide, N-[4-[[(5S)-7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl-
  • Tolvaptan Impurity-Isomer
CAS:
331947-44-5
MF:
C26H25ClN2O3
MW:
448.94
Product Categories:
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
331947-44-5.mol
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(S)-(-)-Tolvaptan Chemical Properties

Melting point:
157-164°C
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
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(S)-(-)-Tolvaptan Usage And Synthesis

Uses

An enantiomer of Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).

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