XL-765,SAR245409
XL-765,SAR245409 Basic information
- Product Name:
- XL-765,SAR245409
- Synonyms:
-
- XL-765,SAR245409
- XL765
- N-[2-[(3,5-Dimethoxyphenyl)amino]quinoxalin-3-yl]-4-[(4-methyl-3-methoxyphenyl)carbonyl]aminophenylsulfonamide
- N-(4-(N-(3-((3,5-DiMethoxyphenyl)aMino)quinoxalin-2-yl)sulfaMoyl)phenyl)-3-Methoxy-4-MethylbenzaMide
- SAR245409
- XL765(Voxtalisib)
- CS-432
- XL-765,SAR245409 USP/EP/BP
- CAS:
- 1123889-87-1
- MF:
- C31H29N5O6S
- MW:
- 599.65686
- Mol File:
- 1123889-87-1.mol
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XL-765,SAR245409 Chemical Properties
- Density
- 1.387
- solubility
- Soluble in DMSO
- form
- Powder
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XL-765,SAR245409 Usage And Synthesis
Uses
XL765 is a low-molecular mass PI3K inhibitor that also inhibits DNA-PK and mTOR.
Definition
ChEBI: XL765 is a sulfonamide obtained by formal condensation of the sulfonic acid group of 4-[(3-methoxy-4-methylbenzoyl)amino]benzenesulfonic acid with the primary aromatic amino group of N-(3,5-dimethoxyphenyl)quinoxaline-2,3-diamine. A dual PI3K/mTOR inhibitor used in cancer treatment. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor, an antineoplastic agent and a mTOR inhibitor. It is a sulfonamide, a quinoxaline derivative, an aromatic amine, a member of benzamides and an aromatic ether.
target
p110α
XL-765,SAR245409Supplier
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
Chembest Research Laboratories Limited
- Tel
- +86-21-20908456
- sales@BioChemBest.com
Shanghai Sunway Pharmaceutical Technology Co., Ltd
- Tel
- 021-51613915-820 13611835272
- mmwang@sunwaypharm.cn
Shanghai Topbiochem Technology Co., Ltd
- Tel
- 021-58170097
- info@topbiochem.com
Chengdu NoVi Biotechnology Co., Ltd.
- Tel
- 028-81458053
- novibiotech@163.com sales@novi-biotech.com