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5-Bromo-1-pentene

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5-Bromo-1-pentene Basic information

Product Name:
5-Bromo-1-pentene
Synonyms:
  • 1-pentene,5-bromo-
  • 2-Pentene,5-bromo-
  • 3-Pentenylbromide
  • 4-Pentenyl bromide
  • 4-Pentenylbromide
  • 5-bromo-1-penten
  • 5-bromo-2-pentene
  • 5-b
CAS:
1119-51-3
MF:
C5H9Br
MW:
149.03
EINECS:
214-281-4
Product Categories:
  • Isoquinolines ,Quinolines ,Quinaldines
  • Alkenyl
  • omega-Functional Alkanols, Carboxylic Acids, Amines & Halides
  • omega-Unsaturated Halides
  • Halogenated Hydrocarbons
  • Organic Building Blocks
  • 1119-51-3
Mol File:
1119-51-3.mol
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5-Bromo-1-pentene Chemical Properties

Melting point:
-106.7°C (estimate)
Boiling point:
126-127 °C/765 mmHg (lit.)
Density 
1.258 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.463(lit.)
Flash point:
30 °C
storage temp. 
2-8°C
solubility 
Chloroform, Ethyl Acetate
form 
Oil
color 
Clear Colourless
Specific Gravity
1.258
Water Solubility 
Immiscible with water.
BRN 
506077
InChIKey
LPNANKDXVBMDKE-UHFFFAOYSA-N
CAS DataBase Reference
1119-51-3(CAS DataBase Reference)
NIST Chemistry Reference
1-Pentene, 5-bromo-(1119-51-3)
EPA Substance Registry System
1-Pentene, 5-bromo- (1119-51-3)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
10-36/37/38
Safety Statements 
26-24/25-16
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
8
TSCA 
Yes
HazardClass 
3
PackingGroup 
II
HS Code 
29033036

MSDS

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5-Bromo-1-pentene Usage And Synthesis

Description

5-Bromo-1-pentene is an organic compound with a molecular weight of 149.03. The formula of this compound is C5H9Br. It is a colorless, transparent liquid. The molecular structure of this molecule contains both double bonds and bromine atoms, giving it the properties of olefins and halogenated hydrocarbons. It serves as the starting material for the synthesis of DL-histrionicotoxin and phenyl-ketone fatty acids. Additionally, it is a fundamental chemical and pharmaceutical intermediate, finding wide applications in the fields of medicine, pesticides, and material chemistry.

Chemical Properties

Clear colorless to yellow liquid

Uses

5-Bromo-1-pentene is widely utilized in the stereoselective synthesis of 7alpha-(3-carboxypropyl) estradiol. It plays an important role as starting material in the synthesis of a variety of compounds including DL-histrionicotoxin and benzophenone containing fatty acids.

Synthesis Reference(s)

Tetrahedron, 28, p. 675, 1972 DOI: 10.1016/0040-4020(72)84031-6

Synthesis

1,5-Dibromopentane (100 Kg), N, N-dimethylformamide (100 Kg), and hexamethylphosphoramide (6.2 Kg) were stirred and mixed, and then heated in an oil bath at 140°C for 4 h. Atmospheric distillation collects the fractions, and the collected fractions are washed twice with 100 Kg brine. The organic liquid is distilled to obtain product 5-Bromo-1-pentene.

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