MK-8617 Chemical Properties

Density 

1.32±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMSO:5.67(Max Conc. mg/mL);12.79(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.56(Max Conc. mM)
DMF:1.0(Max Conc. mg/mL);2.25(Max Conc. mM)

form 

A solid

pka

5.54±0.50(Predicted)

color 

White to off-white

MK-8617 Usage And Synthesis

Uses

MK-8617 is a potent, selective and bioavailable hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) inhibitor used in the treatment of anemia.

MK-8617(1187990-87-9)Related Product Information

• N-{4-[(2-Aminopyridin-4-yl)oxy]-3-fluorophenyl}-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
• N-ACETYL-ALPHA-D-GLUCOSAMINE
• N-BOC-HEXAHYDRO-5-OXOCYCLOPENTA[C]PYRROLE
• N-BOC-6-azaspiro[3.4]octan-2-ol
• CP-456773 sodium
• N-(5-((5-(4-Acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl)thio)thiazol-2-yl)-4-(((3,3-dimethylbutan-2-yl)amino)methyl)benzamide
• N-[(1R)-1-(Aminomethyl)-2-[(3S)-tetrahydro-2H-pyran-3-yl]ethyl]-N-methylcarbamic acid tert-butyl ester
• N,N'-[1,2-Ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)glycine 1,1'-bis[2-(octyloxy)ethyl] ester
• N-BOC-cis-4-fluoro-L-proline
• MG-132
• SRT1720
• N-(8-Benzyl-8-azabicyclo[3.2.1]oct-3-yl-exo)-2-methylpropanamide
• N-Boc-3-piperidineacetic acid
• N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine
• N-Boc-exo-3-aminotropane
• N-Boc-endo-3-aminotropane
• N-(3-HYDROXYPROPYL)ETHYLENEDIAMINE