Basic information Safety Supplier Related

MK-8617

Basic information Safety Supplier Related

MK-8617 Basic information

Product Name:
MK-8617
Synonyms:
  • N-[BIS(4-METHOXYPHENYL)METHYL]-6-OXO-2-PYRIDAZIN-3-YL-1H-PYRIMIDINE-5-CARBOXAMIDE
  • MK 8617;MK8617
  • CS-2700
  • N-(bis(4-methoxyphenyl)methyl)-6-oxo-2-(pyridazin-3-yl)-1,6-dihydropyrimidine-5-carboxamide
  • 5-Pyrimidinecarboxamide,N-[bis(4-methoxyphenyl)methyl]-1,6-dihydro-6-oxo-2-(3-pyridazinyl)-
  • MK-8617
  • N-(bis(4-Methoxyphenyl)Methyl)-4-hydroxy-2-(pyridazin-3-yl)pyriMidine-5-carboxaMide
  • MK-8617,MK 8617,HIF-PH,inhibit,Hypoxia-inducible factors,HIFs,Inhibitor,HIF/HIF Prolyl-Hydroxylase
CAS:
1187990-87-9
MF:
C24H21N5O4
MW:
443.45
Mol File:
1187990-87-9.mol
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MK-8617 Chemical Properties

Density 
1.32±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:5.67(Max Conc. mg/mL);12.79(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.56(Max Conc. mM)
DMF:1.0(Max Conc. mg/mL);2.25(Max Conc. mM)
form 
A solid
pka
5.54±0.50(Predicted)
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MK-8617 Usage And Synthesis

Uses

MK-8617 is a potent, selective and bioavailable hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) inhibitor used in the treatment of anemia.

MK-8617Supplier

Nanjing Habo Medical Technology Co., Ltd.
Tel
025-85760892 13376090521
Email
sales@habotech.com
ShangHai Onsyn-Chemical Technology Co., Ltd.
Tel
021-58359326 13124831025
Email
angsihuaxue@126.com
shanghai cooperpharm co.,LTD .
Tel
+86-021-58975553
Email
sales@cooperpharm.com
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Email
info@efebio.com
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MK-8617(1187990-87-9)Related Product Information