Artanin
Artanin Basic information
- Product Name:
- Artanin
- Synonyms:
-
- Artanin
- 5,7-Dimethoxy-8-[(3-methyl-2-butenyl)oxy]-2H-1-benzopyran-2-one
- 5,7-dimethoxy-8-(3-methylbut-2-enoxy)chromen-2-one
- 2H-1-Benzopyran-2-one, 5,7-dimethoxy-8-[(3-methyl-2-buten-1-yl)oxy]-
- CAS:
- 96917-26-9
- MF:
- C16H18O5
- MW:
- 290.31112
- Mol File:
- 96917-26-9.mol
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Artanin Chemical Properties
- Melting point:
- 104-107 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))
- Boiling point:
- 460.5±45.0 °C(Predicted)
- Density
- 1.168±0.06 g/cm3(Predicted)
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Artanin Usage And Synthesis
Uses
Artanin is a coumarin, has biological activities related to Alzheimer’s disease. Artanin exerts function including AChE inhibitory and AChE- and self-induced amyloid beta (Aβ) aggregation inhibitory activities, with IC50s of 51 μM, 98 μM, and 124 μM, respectively[1].
IC 50
AChE: 51 μM (IC50)
References
[1] Takomthong P, et al. Structure-Activity Analysis and Molecular Docking Studies of Coumarins from Toddalia asiatica as Multifunctional Agents for Alzheimer's Disease. Biomedicines. 2020 May 2;8(5):107. DOI:10.3390/biomedicines8050107
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