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Cophylline

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Cophylline Basic information

Product Name:
Cophylline
Synonyms:
  • Cophylline
  • Vinca alkaloid III-121C
  • [8,15'-Biaspidospermidine]-3,3'-dicarboxylicacid,2,2',3,3'-tetradehydro-6',7':7,16'-diepoxy-6,15-dihydroxy-16,17-dimethoxy-,dimethyl ester, (5a,6b,7a,8a,12R,19a)-(5'a,6'b,7'b,12'R,19'a)-
  • [8,15'-Biaspidospermidine]-3,3'-dicarboxylic acid, 2,2',3,3'-tetradehydro-6',7':7,16'-diepoxy-6,15-dihydroxy-16,17-dimethoxy-, dimethyl ester, (5α,6β,7α,8α,12R,19α)-(5'α,6'β,7'β,12'R,19'α)-
  • Vincristine Impurity 10
CAS:
142741-24-0
MF:
C44H50N4O10
MW:
794.9
Mol File:
142741-24-0.mol
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Cophylline Chemical Properties

Density 
1.53±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
pka
10.73±0.70(Predicted)
form 
Solid
color 
Off-white to light yellow
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Cophylline Usage And Synthesis

Uses

Conophylline can be used in pharmacological activity and therapeutic use of differentiation of adipose-derived stem cells into functional islet-like cells using conophlline and nicotinamide.

in vivo

Conophylline (0.9 mg/kg; p.o.; daily; for 12 weeks) attenuates formation of the liver fibrosis induced by TAA in vivo[2].

Animal Model:Sprague-Dawley rats (70-80 g)[2]
Dosage:0.9 mg/kg
Administration:Oral administration; daily; for 12 weeks
Result:Attenuated formation of the liver fibrosis induced by TAA.

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