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Myriceric acid B

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Myriceric acid B Basic information

Product Name:
Myriceric acid B
Synonyms:
  • Myriceric acid B
  • Wax fruit myric acid B
  • Olean-12-en-28-oic acid,27-[[(2E)-3-(3,4-dihydroxyphenyl)-1- oxo-2-propenyl]oxy]-3-hydroxy-,(3a)-
  • Olean-12-en-28-oic acid, 27-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3-hydroxy-, (3β)-
CAS:
55497-79-5
MF:
C39H54O7
MW:
634.84
Mol File:
55497-79-5.mol
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Myriceric acid B Usage And Synthesis

Uses

Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41. Myriceric acid B is an antitumor agent[1][2].

IC 50

HIV-1: 8.3±0.2 μg/mL (IC50, infection of HIV-1 Env pseudovirus)

References

[1] Eom HJ, et al. Cytotoxic Triterpenoids from the Barks of Betula platyphylla var. japonica. Chem Biodivers. 2017 Apr;14(4). DOI:10.1002/cbdv.201600400
[2] Xia C, et al. The anti-HIV-1 entrance activity and mechanism of action of myriceric acid B from Rhoiptelea chiliantha Diels et Hand-Mazz. Chinese Pharmacological Bulletin, 2010: 447-452.

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